Evidence map›Paper›PMID 41140917›Full record

ArticleIDCases2025

Rapidly progressive pseudomembranous Aspergillus tracheobronchitis diagnosed by bronchoscopy in a mechanically ventilated immunocompromised patient: A case report.

Ryusuke Maruta, Genki Yoshimura, Kazuya Okada, Jun Makino

Abstract readCase Reports
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryusuke MarutaDepartment of Respiratory Medicine, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
Genki YoshimuraDepartment of Critical Care Medicine, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
Kazuya OkadaDepartment of Critical Care Medicine, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
Jun MakinoDepartment of Critical Care Medicine, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus tracheobronchitis (AT) is a rare and severe manifestation of invasive aspergillosis, primarily affecting immunocompromised patients. The pseudomembranous subtype is associated with high mortality, particularly among those requiring mechanical ventilation. We report the case of an 86-year-old woman with nephrotic syndrome receiving corticosteroid and cyclosporine therapy who developed respiratory failure following emergency surgery for sigmoid colon perforation. After being admitted to the intensive care unit and placed on mechanical ventilation, she developed worsening oxygenation on ICU day 7. Chest computed tomography revealed bilateral ground-glass opacities, and serum β-D-glucan levels were elevated, initially raising suspicion for Pneumocystis pneumonia. Bronchoscopy on ICU day 12 showed no airway abnormalities, but repeat bronchoscopy on day 14 demonstrated extensive tracheal pseudomembranes and a yellowish endobronchial plaque. Cytological and microbiological examinations confirmed

Indexed as

Aspergillus TracheobronchitisBronchoscopyImmunocompromised hostMechanical ventilationPseudomembrane

Identifiers

PMID41140917
PMCPMC12553014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.