ArticleOphthalmology science2026
Potential Negative Feedback between Age and Baseline Axial Length on Axial Elongation in High Myopia.
Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- The Effect of Three-Dimensional Ocular Shape on Longitudinal Biometric Changes: A Six-Year Follow-Up Study.Translational vision science & technology · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the axial elongation in highly myopic eyes and assess the effects of age, sex, baseline axial length (AL), cataract surgery (CS), pathologic myopia (PM), baseline intraocular pressure (IOP), and genetic risk scores (GRSs). Design: Retrospective cohort study. Participants: This study included 614 eyes from 367 individuals with high myopia. Methods: The study assessed axial elongation rates and their associations with age, sex, baseline AL, CS, PM, and baseline IOP including potential interactions among these factors. Additionally, the study examined whether incorporating GRS improved the predictive model for axial elongation. Main Outcome Measures: Axial elongation rate in highly myopic eyes. Results: The study included 367 participants (217 [59.1%] females, 150 [40.9%] males) with a mean age of 58.9 ± 14.4 years and a mean AL of 28.6 ± 2.0 mm. The mean follow-up duration was 4.7 ± 2.7 years, and the average axial elongation rate was 0.031 ± 0.030 mm/year. Cataract surgery was associated with significantly slower axial elongation ( Conclusions: Axial elongation persists in highly myopic eyes (0.031 mm/year) but slows over time, owing to baseline AL-age interactions. Genetic risk scores have limited predictive utility in adulthood. This highlights the need for further research on genetic and environmental determinants of myopia progression. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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