ArticleJournal of oral biology and craniofacial research
Efficacy of chitosan dressing as a local haemostatic agent in the management of dental extractions in patients on antiplatelet therapy. A prospective randomized study.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Local Hemostasis as the Critical Enabler for Safe Antithrombotic Therapy in Dentistry-Navigating Future Frontiers and Innovative Concepts.Journal of clinical medicine · 2026Review
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction: Dental extractions in patients on antiplatelet therapy pose a bleeding risk. Current guidelines support continuing antiplatelet therapy during surgery, but effective local hemostasis is crucial. Chitosan, a biopolymer with haemostatic, antimicrobial, and wound-healing properties, may offer advantages over cotton gauze. This study evaluated chitosan dressing vs. standard gauze during dental extractions in patients on antiplatelet therapy. Methodology: A prospective randomized study was conducted over 18 months at the Department of Oral and Maxillofacial Surgery, Government College of Dentistry, Indore, with 100 patients on antiplatelet therapy. Extraction sites were randomly assigned to Group A (chitosan) or Group B (cotton gauze). The primary outcome was time to hemostasis, with secondary outcomes including pain (VAS), Landry healing index, postoperative bleeding, and complications. Data were analyzed using SPSS v25.0. Results: Group A showed significantly faster hemostasis (median 0.67 min) compared to Group B (median 4.5 min; p < 0.001). Bleeding ceased within 3 min in all Group A sockets vs. 11 % in Group B (p < 0.001). Group A also had lower pain scores and higher healing index values at Day 7 (both p < 0.001). Dry socket incidence was low and similar between groups. Conclusion: Chitosan dressing appears to be a promising adjunct for achieving rapid hemostasis, reducing postoperative discomfort, and improving early healing following dental extractions in patients on antiplatelet therapy. Larger multicenter studies with longer follow-up are recommended to confirm these findings and explore broader clinical applications.
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