ArticleJournal of oral biology and craniofacial research
Quantitative evaluation of spatial heterogeneity in dentin attrition using combined spectroscopic and elemental profiling.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Age-related attrition in dentin is associated with gradual mineral loss and collagen degradation, affecting its structural and functional integrity. However, there remains a need for standardized, quantitative indices to assess these degenerative changes. Objective: This study aimed to evaluate the structural, chemical, and elemental changes in healthy versus attrited dentin using a multimodal analytical approach and to introduce novel quantitative indices for assessing dentin degradation. Methods: Human teeth exhibiting signs of attrition were collected, processed, and analyzed using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), inductively coupled plasma mass spectrometry (ICP-MS). Four novel indices-Crystallinity Loss Index (CLI), Mineral Integrity Index (MII), Collagen Degradation Ratio (CDR), and Structural Degradation Index (SDI)-were developed and applied. Results: Attrited dentin showed significantly reduced crystallinity (CLI = 25.2 %), decreased mineral integrity (MII = 0.38), and marked collagen loss (CDR = 0.60) compared to healthy samples. Elemental analysis revealed a decreased Ca/P ratio and lower concentrations of Zn and Sr, with elevated Fe and Cu levels in aged dentin. The SDI (0.237) provided a composite representation of overall dentin degradation. Conclusion: The combined use of spectroscopic and elemental analyses, along with the application of novel quantitative indices, enables a robust evaluation of dentin degradation associated with attrition. These metrics hold potential in clinical diagnosis, forensic dentistry, and restorative treatment planning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.