Evidence map›Paper›PMID 41140836›Full record

ArticleFood chemistry. Molecular sciences2025

Multi-omics study uncovered key differences in taste and nutritional quality among three distinct bitter gourd (

Shudan Xue, Muhammad Sajjad, Meijiang Zhou, Yingchao Xu, Wenlong Luo, Yingyin Lin, Qingmin Jin, Xiaoming Zheng, Yujuan Zhong

Abstract read
In one paragraph

Article in Food chemistry. Molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shudan XueGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Muhammad SajjadGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Meijiang ZhouGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Yingchao XuGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Wenlong LuoGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Yingyin LinGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Qingmin JinGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Xiaoming ZhengGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.
Yujuan ZhongGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bitter gourd is a widely consumed vegetable recognized for its diverse health-promoting functions. Bitter-melon cultivars (D, B, Q) differ in consumer preferences due to quality variations. Given the lack of studies on flavor, color, and nutrition coregulation in bitter gourd, we hypothesized that these traits are driven by genetic modulation of bitterness-linked pathways. This study used comparative trans-meta-analysis to systematically explore the metabolic and molecular basis of these quality traits. The metabolome analysis shows the 8R-dihydrodehydrodiconferyl alcohol 4-O-β-D-glucopyranoside (phenolic) and borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside (saponin), geranyl 3-O-xylopyranosyl-glucopyranoside (saponin) all are highly induced in B and Q, while, glycosylated terpenoids (e.g. goyaglycoside, kuguaglycoside) were markedly higher in cv. D compared to other cultivars, that may cause the concurrent superior traits in D. Accordingly, DEGs encoding structural enzymes i.e. sugars (

Indexed as

ColorFlavorHealthMetabolomeMolecular regulationTranscriptomeVegetable

Identifiers

PMID41140836
PMCPMC12553077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.