Evidence map›Paper›PMID 41140744›Full record

ArticleJournal of inflammation research2025

Biomarker Quantification of Gut Dysbiosis-Derived Inflammation: A Review.

Leqi Lin, Jacob George, Guozhen Liu

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leqi LinIntegrated Devices and Intelligent Diagnosis (ID2) Laboratory, CUHKSZ-Boyalife Regenerative Medicine Engineering Joint Laboratory, School of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, People's Republic of China.
Jacob GeorgeStorr Liver Centre, Westmead Institute of Medical Research, University of Sydney and Department of Gastroenterology and Hepatology, Westmead Hospital, Westmead, NSW, 2145, Australia.ORCID 0000-0002-8421-5476
Guozhen LiuIntegrated Devices and Intelligent Diagnosis (ID2) Laboratory, CUHKSZ-Boyalife Regenerative Medicine Engineering Joint Laboratory, School of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, People's Republic of China.ORCID 0000-0002-0556-6404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut dysbiosis, an alteration or imbalance in the composition and function of the gut microbiome can lead to a range of health issues. Inflammation in this setting leads to increased permeability of the intestinal barrier and the activation of immune responses which contributes to a range of inflammatory, autoimmune and metabolic diseases. Therefore, precise quantification of gut-derived inflammation is important to gain insights into the development and progression these diseases and to develop treatments. This review highlights the underlying mechanisms leading to gut inflammation and the markers of gut dysbiosis mediated inflammation. We then discuss strategies including disposable and wearable biosensing devices, biomedical imaging, sequencing and AI-based methods for the quantification of dysbiosis-derived inflammation. Challenges and future perspectives for quantification of gut dysbiosis mediated inflammation are proposed.

Indexed as

cytokinesdisposable devicegut dysbiosisinflammationingestible deviceslipopolysaccharide

Identifiers

PMID41140744
PMCPMC12553352

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.