Evidence map›Paper›PMID 41140673›Full record

ArticleFrontiers in medicine2025

Diagnostic value of metagenomic next-generation sequencing in atypical brucellosis: a case report.

Dungaowa Ao, Xinle Li, Guoliang Zhang, Huiyu Ma, Lijuan Yang, Hui Tian, Shuxia Ao, Jin Feng, Wanru Geng

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dungaowa AoAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.
Xinle LiThe Fourth Affiliated Hospital, Anhui Medical University, Hefei, China.
Guoliang ZhangAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.
Huiyu MaAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.
Lijuan YangAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.
Hui TianAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.
Shuxia AoAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.
Jin FengTongliao Mongolian Medical Hospital, Tongliao, China.
Wanru GengAffiliated Hospital, Inner Mongolia Minzu University, Tongliao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brucellosis with atypical presentations, such as submandibular abscess without fever, is frequently misdiagnosed. Methods: Metagenomic next-generation sequencing (mNGS) was applied to pus samples from a 47-year-old female with a treatment-refractory submandibular abscess and a history of livestock exposure; results were confirmed serologically. Results: Within 48 h, mNGS identified Conclusion: This case highlights that mNGS, combined with a thorough epidemiological history, can resolve diagnostic dilemmas in atypical brucellosis, guide precise treatment, and mitigate antibiotic misuse.

Indexed as

Brucella suisbrucellosishigh-throughput sequencingmetagenomic next-generation sequencingsubmandibular space infection

Identifiers

PMID41140673
PMCPMC12549301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.