ArticleFrontiers in medicine2025
Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in elderly patients undergoing laparoscopic surgery.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia.Healthcare (Basel, Switzerland) · 2026Review
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Authors and funding
7 authors.
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Abstract
Background: This study examines the effect of permissive hypercapnia (PH) on cerebral oxygenation (rSO Methods: This retrospective study analyzed data from elderly patients who underwent laparoscopic surgery with PH mechanical ventilation or conventional ventilation (CV) ventilation strategies between 2019 and 2024. The individuals were separated into two groups as stated by the intraoperative anesthesia method, and equal numbers in each group. A total of 550 patients were initially screened for eligibility, of whom 100 were excluded based on predefined criteria. The final analysis included 450 patients, with 225 receiving PH mechanical ventilation (PH group) and 225 receiving conventional ventilation (CV, control group). Postoperative cognitive dysfunction (POCD), postoperative regional cerebral oxygen saturation (rSO Results: Permissive hypercapnia was associated with significantly improved intraoperative cerebral oxygenation (rSO Conclusion: Permissive hypercapnia significantly improves rSO
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