Evidence map›Paper›PMID 41140581›Full record

ArticleIBRO neuroscience reports2025

Napping restores working memory and brain activation impaired by sleep deprivation.

Anping Ouyang, Jun Jiang, Lin Wu, Xinxin Lin, Lingling Wang, Qiutao Yan, Xuqian Diao, Yan Li, Yuanqiang Zhu, Lingli Zeng and 4 more

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In one paragraph

Article in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anping OuyangDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Jun JiangDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Lin WuDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Xinxin LinDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Lingling WangDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Qiutao YanDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Xuqian DiaoDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Yan LiDepartment of Psychology, School of Social Sciences, Tsinghua University, Beijing, China.
Yuanqiang ZhuDepartment of Radiology, Xijing Hospital, The Fourth Military Mediacl University, Xi'an, China.
Lingli ZengCollege of Intelligence Science and Technology, National University of Defense Technology, Changsha, China.
Jiaxi PengCollege of Teachers, Chengdu University, Chengdu, China.
Qianqian DongKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
Wei HeDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.
Peng FangDepartment of Military Medical Psychology, The Fourth Military Mediacl University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sleep deprivation (SD) impairs working memory (WM), yet the restorative potential of brief daytime naps remains underexplored. This study examines how naps counteract SD-induced WM deficits through behavioral and neuroimaging mechanisms, focusing on task-positive networks and default mode network (DMN) dynamics. Method: A within-subject fMRI study employed 2-back WM tasks in 50 participants under three conditions: baseline wakefulness, post-30h SD, and post-nap recovery. Behavioral metrics (reaction times, accuracy) and fMRI activation patterns were analyzed using repeated-measures ANOVA and mixed-effects models to assess SD and nap effects. Result: Naps partially restored SD-induced WM declines, improving reaction times and accuracy. Post-SD, reduced activation in the cerebellum, insula, and thalamus (attention/executive regions) rebounded post-nap. SD weakened DMN suppression (middle frontal gyrus, precuneus, superior temporal gyrus), with maximal DMN suppression post-nap. Improved WM performance correlated with reactivated task-positive networks. Conclusion: Daytime naps mitigate SD-related WM deficits by rebalancing task-positive network activation (cerebellum, thalamus) and enhancing DMN suppression. These findings elucidate neurophysiological mechanisms of sleep-cognition interactions, supporting naps as a practical intervention for SD-induced cognitive impairment.

Indexed as

brain region activationdaytime nappingsleep deprivationworking memory

Identifiers

PMID41140581
PMCPMC12546891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.