Evidence map›Paper›PMID 41140576›Full record

ReviewCurrent research in food science2025

Schiff base crosslinking in biopolymeric food packaging films: Dynamic covalent chemistry for advanced food preservation systems.

Guihong Fang, Bangdi Liu, Wanli Zhang, Ajahar Khan, Zohreh Riahi, Parya Ezati, Swarup Roy, Seid Mahdi Jafari

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current research in food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biomimetic Design of Biopolymer-Based Water-Resistant Food Packaging Materials.Comprehensive reviews in food science and food safety · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guihong FangSchool of Public Health, International Collaborative Research Center for the Development and Utilization of Tropical Food for Special Medical Purpose, Hainan Medical University, Haikou, 571199, China.
Bangdi LiuAcademy of Agricultural Planning and Engineering, MARA, Beijing, 100125, China.
Wanli ZhangSchool of Food Science and Engineering, Hainan University, Haikou, 570228, China.
Ajahar KhanDepartment of Food and Nutrition, BioNanocomposite Research Center, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea.
Zohreh RiahiDepartment of Food and Nutrition, BioNanocomposite Research Center, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea.
Parya EzatiDepartment of Food Science, University of Guelph, ON, N1G2W1, Canada.
Swarup RoyDepartment of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara, Punjab, 144411, India.
Seid Mahdi JafariFaculty of Food Science and Technology, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biopolymeric films (BFs) offer sustainable packaging alternatives but face limitations in mechanical strength and moisture resistance. This review explores dynamic covalent chemistry via Schiff base reactions (SBRs) as a transformative strategy to enhance BFs. Crosslinking amino-rich biopolymers (e.g., chitosan, gelatin) with aldehyde donors (e.g., dialdehyde polysaccharides, plant aldehydes) improves film stability, barrier properties, and stimuli-responsive behavior. Plant aldehydes serve dual roles as crosslinkers and antimicrobial agents, enabling pH-triggered release to combat spoilage. Advances in polysaccharide/protein-based films demonstrate efficacy in preserving fruits, vegetables, and meats. Innovations like pH-sensitive indicators and respiration-triggered release underscore SBR-engineered films' versatility for active packaging. Challenges in scalability, safety, and industrial integration remain. This work provides a roadmap for next-generation packaging balancing performance, sustainability, and precision preservation.

Indexed as

ChitosanControlled releaseCross linkingGelatinPackaging film

Identifiers

PMID41140576
PMCPMC12549926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.