Evidence map›Paper›PMID 41140484›Full record

ArticleInfection and drug resistance2025

Environmental Persistence of High-Risk KPC-Producing ST463

Weixiao Shi, Piaopiao Zhang, Haiting Feng, Tianxiang Ge, Yunbo Chen, Yan Jiang, Ping Shen, Lingmei Ni, Chengbo Yu, Tingting Qu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Weixiao Shi *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Piaopiao Zhang *State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Haiting Feng *Infection Control Department, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Tianxiang GeInfection Control Department, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Yunbo ChenState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.ORCID 0000-0002-5843-1386
Yan JiangDepartment of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Ping ShenState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Lingmei NiInfection Control Department, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Chengbo YuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Tingting QuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to investigate the distribution and characteristics of high-risk, difficult-to-treat resistant Patients and Methods: This 11-month study investigated Carbapenem-resistant Results: A total of 54 CRPA were isolated from the environment and inpatients in ICUs and classified into 25 STs, with ST463 identified as the predominant ST (13/54, 24.07%). All 13 ST463 PA isolates belonged to DTR-PA, including 4 from patients and 9 from environments primarily from wastewater dumping pools. All ST463-DTR-PA isolates carried Conclusion: KPC-ST463-DTR-PA can widely colonize in ICU environment. Contamination and incomplete disinfection in humid environments may provide evolutionary opportunities for ST463-DTR-PA. Hence, it's worth our vigilance about the growing prevalence of ST463-DTR-PA in East China's ICUs. Meanwhile, it is important to strengthen the management of the ICU environment, especially water reservoirs, and even to promote the management of patients without water.

Indexed as

difficult-to-treat resistant Pseudomonas aeruginosaICUresistanceST463transmissionvirulence

Identifiers

PMID41140484
PMCPMC12553440

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.