Evidence map›Paper›PMID 41140368›Full record

ArticleJournal of diabetes research2025

Impact of Exendin-4 on the Differentiation and Function of Transplanted Porcine Neonatal Pancreatic Cell Clusters in Diabetic Nude Mice.

Jyuhn-Huarng Juang, Chen-Yi Chen, Chen-Wei Kao, Chen-Ling Chen, Wan-Chun Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jyuhn-Huarng JuangDivision of Endocrinology and Metabolism, Department of Internal Medicine and Center for Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0003-1544-6059
Chen-Yi ChenDivision of Endocrinology and Metabolism, Department of Internal Medicine and Center for Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chen-Wei KaoDivision of Endocrinology and Metabolism, Department of Internal Medicine and Center for Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chen-Ling ChenDivision of Endocrinology and Metabolism, Department of Internal Medicine and Center for Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Wan-Chun LiInstitute of Oral Biology, College of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID https://orcid.org/0000-0003-0481-4215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine neonatal pancreatic cell clusters (NPCCs) are a promising and abundant source for islet transplantation owing to their ability to secrete insulin and proliferative potential. However, a significant limitation is the delayed normalization of blood glucose following transplantation, largely attributed to incomplete

Indexed as

Cell DifferentiationDiabetes Mellitus, ExperimentalExenatideHypoglycemic AgentsInsulin-Secreting CellsIslets of Langerhans TransplantationPancreasPeptidesVenomsAnimalsAnimals, NewbornBlood GlucoseGlucagonHomeodomain ProteinsInsulinMaleBlood GlucoseExenatideGlucagonHomeodomain ProteinsHypoglycemic AgentsInsulinpancreatic and duodenal homeobox 1 proteinPeptidesSOX9 Transcription FactorTrans-ActivatorsVenomsdifferentiationexendin-4glycemic controlporcine neonatal pancreatic cell clusterstransplantation

Identifiers

PMID41140368
PMCPMC12552079

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.