Evidence map›Paper›PMID 41140354›Full record

ArticleJAAD international2025

Efficacy and safety of twice- or thrice-weekly dutasteride versus daily finasteride in men with androgenetic alopecia: A randomized, investigator-blinded, active-controlled, parallel-group pilot study.

Varalee Sereepanpanich, Saranya Khunkhet, Salinee Rojhirunsakool, Montree Udompataikul

Abstract read
In one paragraph

Article in JAAD international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Varalee SereepanpanichDepartment of Dermatology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Saranya KhunkhetDepartment of Dermatology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Salinee RojhirunsakoolDepartment of Dermatology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Montree UdompataikulDepartment of Dermatology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dutasteride is sometimes used in treating male androgenetic alopecia; however, published data on intermittent regimens are scant. Objective: To evaluate efficacy and safety of twice-weekly and thrice-weekly regimens of dutasteride, and to compare with finasteride, in men with androgenetic alopecia. Methods: Sixty men, aged 21 to 60 years, were randomized to receive dutasteride 0.5 mg twice weekly, dutasteride 0.5 mg thrice weekly, or finasteride 1 mg daily for 24 weeks. Efficacy was evaluated by changes of hair density and diameter using videodermoscopy, and global photographic assessment. Results: Hair density and diameter significantly increased after treatment in 3 groups (all Limitations: Unblinded participants to treatment allocation. Conclusion: Twice-weekly and thrice-weekly regimens of dutasteride increased hair growth and were well-tolerated. Although thrice-weekly dutasteride was significantly superior to twice-weekly dutasteride, in terms of hair density and diameter, thrice-weekly dutasteride did not significantly increase hair count over finasteride 1 mg daily.

Indexed as

5α-reductase inhibitorsdutasterideintermittent regimenslow-dose dutasteridemale androgenetic alopeciamale pattern hair loss

Identifiers

PMID41140354
PMCPMC12547282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.