ArticleFrontiers in oral health2025
Xerostomia in primary care: a register-based study of prevalence, medication categories, and associated risk factors.
Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Xerostomia and Oral Health-Related Quality of Life in Chilean Older Adults Living in Long-Term Care Facilities.Gerodontology · 2026Article
- Frequency of salivary flow rate measurements in Sweden 2008-2024.Acta odontologica Scandinavica · 2026Article
- Geriatric Oral Health in the United States: Current Status and Challenges.Geriatrics (Basel, Switzerland) · 2026Review
- Prevalence, predictors and severity of xerostomia in adult patients in general dental care.Frontiers in oral health · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Xerostomia, the subjective sensation of oral dryness, is often associated with reduced salivary secretion. Xerostomia is a prevalent side effect to numerous medications but also found associated with aging and female sex. The objective of the study is to estimate the prevalence of xerostomia in association with the number and type of medications used by adults in the region of Västra Götaland, Sweden. Materials and methods: Data on age, sex, and medication use in patients diagnosed with xerostomia, using International Classification of Disease (ICD) 10 code 11.7 and R68.2 was obtained from the health care database in the region of Västra Götaland, Sweden (Vega). Prevalence of xerostomia diagnosis was estimated according to the type and number of medications consumed, stratified by age and sex. Results: The overall prevalence of xerostomia diagnosis was 0.23%. Medication was strongly associated with xerostomia, with the highest percentage of diagnosis observed in patients taking medications for treatment of metabolic diseases and diseases in alimentary tract (16.07%), the nervous system (16.04%), and the cardiovascular system (12.63%). Xerostomia was also associated with the number of medications. Polypharmacy (concomitant intake of five or more medications) and aged over 71 years was associated with 9.68-times higher odds for xerostomia ( Conclusions: The findings emphasize a strong association between medication use, particularly polypharmacy, and xerostomia, with substantial variations across age, sex, and medication categories. Despite the high risk, a low prevalence of xerostomia diagnosis was reported in primary care settings. The findings suggest a need for increased clinical awareness and routine assessment to improve detection and management.
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