Evidence map›Paper›PMID 41140298›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2025

Long-Term Outcomes of Pediatric Kidney Transplants From DCD and DBD Donors: A Comparative OPTN Study.

Alicia Paessler, Joe Brierley, Marion Siebelink, Ioannis Loukopoulos, Nicos Kessaris, Jelena Stojanovic

Abstract readComparative Study
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Potential for donation after circulatory death in Germany: a multicenter retrospective study at seven university hospitals.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alicia PaesslerGreat Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
Joe BrierleyGreat Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
Marion SiebelinkTransplant Centre, University Medical Center Groningen, Groningen, Netherlands.
Ioannis LoukopoulosGreat Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
Nicos KessarisGreat Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
Jelena StojanovicGreat Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.

Funding

HRSA HHS HHSH250-2019-00001C
6 · The paper itself

Abstract

We compared the long-term outcomes of pediatric kidney transplants from DCD and DBD donors over a 33-year period in the USA. Data were retrieved and analysed on kidney transplants from deceased donors in paediatric recipients in 1994-2020 from the OPTN. Data were compared between those receiving kidney transplants from DBD and DCD donors. There were 11,071 paediatric kidney transplants from deceased donors including 350 from DCD donors. DCD transplants were more likely to have delayed allograft function (20.1% vs. 11.9%, p < 0.01). However, there was no significant difference in allograft or patient survival between transplants from DBD and DCD donors at 10 years (56% vs. 55%, p = 0.76 and 90% vs. 91%, p = 0.89). We describe the largest cohort of pediatric DCD kidney transplant recipients in the literature. We showed that despite higher rates of delayed allograft function in DCD transplants, long-term outcomes were not significantly different. Kidney transplants from DCD donors are a viable option and should be offered to children comparable to DBD kidneys as their long-term outcomes do not differ. DCD transplantation is illegal in some countries, however, it offers an opportunity to increase the number of transplants for children; this data should be considered in ongoing policy discussions.

Indexed as

Kidney TransplantationTissue DonorsAdolescentChildChild, PreschoolDelayed Graft FunctionFemaleGraft SurvivalHumansInfantMaleRetrospective StudiesTissue and Organ ProcurementTreatment OutcomeUnited StatesDBD donorDCDkidney transplantpediatricregistry

Identifiers

PMID41140298
PMCPMC12548547

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.