Evidence map›Paper›PMID 41140238›Full record

ArticleJournal of the American Chemical Society2025

Twisted Host-Guest Systems Exhibit Superamplification of Asymmetry via Coupled Strong Association and Helicity-Driven Cooperativity.

Nozomu Suzuki, Kazuya Miyata, Yudai Ono, Yutaro Yamasaki, Takeharu Haino

Abstract read
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In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nozomu SuzukiDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Rokko, Nada, Kobe 657-8501, Japan.ORCID 0000-0003-3716-735X
Kazuya MiyataDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Rokko, Nada, Kobe 657-8501, Japan.
Yudai OnoInternational Institute for Sustainability with Knotted Chiral Meta Matter (WPI-SKCM2), Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526, Japan.ORCID 0009-0001-0694-7321
Yutaro YamasakiDepartment of Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526, Japan.
Takeharu HainoInternational Institute for Sustainability with Knotted Chiral Meta Matter (WPI-SKCM2), Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526, Japan.ORCID 0000-0002-0945-2893

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiral host-guest systems are central to applications in chiral separation, chiral sensing, and asymmetric catalysis. Chiral interactions involving multiple guest molecules exhibit three key features: helicity-driven amplification of asymmetry (i.e., chiral amplification), mutually exclusive binding, and extremely high selectivity. Coupling of amplification of asymmetry with the latter two features can lead to a phenomenon that surpasses conventional amplification of asymmetry, which we propose to term 'superamplification of asymmetry'. Despite its potential, no established theoretical framework exists. In this work, we developed three models: a general 1:2 twisted host-guest interaction model; the 1:

Identifiers

PMID41140238
PMCPMC12673596

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.