Evidence map›Paper›PMID 41140061›Full record

ArticleEuropean journal of neurology2025

Association Between Trapezius Muscle Stiffness and Headache Severity in Patients With Tension-Type Headache.

Daisuke Shimada, Eiichi Ishikawa, Takuya Kawai, Yoichi Harada, Toru Hatayama, Takuji Kono, Koichi Okamura, Toshitsugu Terakado, Kiyotaka Toyoda, Shohei Iijima and 2 more

Abstract read
In one paragraph

Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daisuke ShimadaDepartment of Neurosurgery, Koyama Memorial Hospital, Ibaraki, Japan.
Eiichi IshikawaDepartment of Neurosurgery, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.ORCID 0000-0001-9224-9767
Takuya KawaiDepartment of Neurosurgery, Koyama Memorial Hospital, Ibaraki, Japan.
Yoichi HaradaDepartment of Neurosurgery, Mito Brain Heart Center, Ibaraki, Japan.
Toru HatayamaDepartment of Neurosurgery, Mito Brain Heart Center, Ibaraki, Japan.
Takuji KonoDepartment of Neurosurgery, Mito Brain Heart Center, Ibaraki, Japan.
Koichi OkamuraDepartment of Neurosurgery, Koyama Memorial Hospital, Ibaraki, Japan.
Toshitsugu TerakadoDepartment of Neurosurgery, Koyama Memorial Hospital, Ibaraki, Japan.
Kiyotaka ToyodaDepartment of Neurosurgery, Koyama Memorial Hospital, Ibaraki, Japan.
Shohei IijimaDepartment of Neurosurgery, Iijima Clinic, Ibaraki, Japan.
Yuta SasakiDepartment of Neurosurgery, Koyama Memorial Hospital, Ibaraki, Japan.
Satoru MiyawakiDepartment of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTension-type headache (TTH) is one of the most prevalent headache disorders worldwide, yet its underlying pathophysiological mechanisms remain poorly understood. Previous research suggests a potential link between myofascial factors, such as trapezius muscle stiffness, and headache severity. This study investigates the association between upper trapezius muscle stiffness and headache severity in patients with TTH.

methodsWe conducted a cross-sectional analysis of 203 patients diagnosed with TTH, evaluating muscle stiffness using a portable muscle hardness meter and headache severity using the Headache Impact Test-6 (HIT-6) and Migraine Disability Assessment Scale (MIDAS). Logistic regression analysis was performed to identify correlations between muscle stiffness and headache severity, adjusting for age, sex, and other clinical variables.

resultsThe mean muscle stiffness values were 32.5 ± 5.8 on the left and 31.3 ± 5.6 on the right. HIT-6 scores positively correlated with muscle stiffness (β = 0.148), chronic TTH (β = 0.304), and age (β = -0.203). Significant clinical symptoms associated with headache severity included weakness (β = 0.154) and a heavy eyelid sensation (β = 0.154). However, shoulder stiffness and neck pain were not significantly associated with headache severity. Triggers such as stress and weather changes were also identified as significant predictors of headache severity.

conclusionsIncreased trapezius muscle stiffness positively correlates with greater headache severity in TTH patients. Weakness and heavy eyelid sensation may serve as important clinical indicators of headache severity, offering potential insights for improved diagnosis and management.

Indexed as

Superficial Back MusclesTension-Type HeadacheAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSeverity of Illness Indexheadache severity (HIT–6, MIDAS)muscle stiffnessrisk factors and symptomstension‐type headache (TTH)trapezius Muscle/physiology

Identifiers

PMID41140061
PMCPMC12554949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.