Evidence map›Paper›PMID 41139808›Full record

ArticleJournal of cellular and molecular medicine2025

Ferritinophagy Is Involved in the Advanced Glycation End Products-Induced Ferroptosis of Vascular Endothelial Cells in Diabetes Mellitus.

Yi Huang, Yongzhi Jin, Junsheng Hu, Mengfan Li, Ming Tian, Guang Zeng, Rong Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi HuangDepartment of General Surgery, Putuo Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yongzhi JinDepartment of General Surgery, Putuo Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Junsheng HuDepartment of General Surgery, Putuo Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Mengfan LiDepartment of General Surgery, LiQun Hospital, Putuo District, Shanghai, China.
Ming TianDepartment of Burn, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Guang ZengDepartment of General Surgery, Putuo Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Rong HuangDepartment of General Surgery, Putuo Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0000-0001-8029-5184

Funding

National Natural Science Foundation of China 81670752Putuo District Special Disease Construction Project for Lower Limb Arteriosclerosis Obliterans 2024tszb03the 'Xinglin Scholar' Research Promotion Program for Disciplinary Talents at Chengdu University of Traditional Chinese Medicine YYZX2022167
6 · The paper itself

Abstract

This study investigated the role of advanced glycation end products (AGEs) and ferritinophagy-dependent ferroptosis in the pathogenesis of diabetic atherosclerosis obliterans. We investigated the effects of AGEs on ferroptosis and ferritinophagy in HUVECs. The methods employed included the CCK-8 assay, reactive oxygen species (ROS) determination, Fe

Indexed as

AutophagyDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2FerritinsFerroptosisGlycation End Products, AdvancedAnimalsEndothelial CellsGlutathioneHumansHuman Umbilical Vein Endothelial CellsIronLipid PeroxidationMaleOxidative StressRatsFerritinsGlutathioneGlycation End Products, AdvancedIronReactive Oxygen Speciesadvanced glycation end productsdiabetes mellitusferritinophagyferroptosisvascular endothelial cells

Identifiers

PMID41139808
PMCPMC12554625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.