Evidence map›Paper›PMID 41139689›Full record

Trial reportJournal of the American Geriatrics Society2025

Impact of the Tailored Activity Program (TAP) on Depressive Symptoms Among White and Black Dementia Caregivers.

Laura N Gitlin, David L Roth, Katherine Marx

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01892579 (Reducing Agitation in People With Dementia), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01892579 nacompletednot on this map

Reducing Agitation in People With Dementia: the Customized Activity Trial

TypeinterventionalSponsorJohns Hopkins UniversityRan2013 to 2017Enrolled250ConditionsDementiaArmsTailored Activity Program, Home Safety and Education Program
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura N GitlinCollege of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-2869-473X
David L RothSchool of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Katherine MarxSchool of Nursing, Johns Hopkins University, Baltimore, Maryland, USA.

Funding

Reducing Agitation in Dementia Patients at Home: The Customized Activity TrialR01AG041781 · NIA · JOHNS HOPKINS UNIVERSITY · PI GITLIN, LAURA N. · 2012 to 2017
$3.3M
NIA NIH HHS R01 AG041781
6 · The paper itself

Abstract

backgroundDepressive symptoms are common in caregivers of people with dementia, with most interventions targeting their emotional/cognitive stance. Unknown is whether targeting people with dementia's quality of life can improve caregiver mood.

methodsOf 250 caregivers in a single-blind, two-arm randomized trial, we examined a subgroup (N = 94) identifying as White (N = 60) or Black (N = 34) and with elevated depression scores (PHQ-9 ≥ 5) at baseline. Caregivers randomized to the Tailored Activity Program (TAP) received eight home sessions by occupational therapists who provided activities tailored to people with dementia's interests and abilities and instructed caregivers in their use. Caregivers randomized to attention control received eight sessions by research assistants who provided dementia education. The primary outcome was the caregivers PHQ-9 scores (3-months-baseline).

resultsCaregivers were on average 64.6 years old. Most were female (84.0%), college educated (76.5%), and caregiving for about 4 years. More Black than White caregivers were non-spouses (76.5% vs. 40.0%; p < 0.01). At baseline, PHQ-9 scores were similar for Black and White caregivers and in the mild severity range. By 3 months, there was a significant race by treatment interaction effect (p = 0.031), with covariate-adjusted means showing significant decreases in PHQ-9 scores for White caregivers in TAP only (adj. M = -2.3). In pairwise comparisons, White TAP caregivers had greater decreases in PHQ-9 scores than White caregivers in the control group (p = 0.01) whose scores worsened. No differences were observed between Black caregivers in TAP versus controls, although PHQ-9 scores decreased for both groups (p > 0.05). However, both Black and White TAP caregivers were more likely to remit (PHQ-9 < 5) compared to controls by 3-months (odds ratio = 3.24, 95% CI = 1.05-10.14, p = 0.04).

conclusionsEngaging people with dementia in activities improved mood in White caregivers, and both Black and White caregivers benefited from a remission in clinically significant depressive symptoms.

trial registrationClinicaltrials.gov identifier: # NCT01892579.

Indexed as

Black or African AmericanCaregiversDementiaDepressionOccupational TherapyWhite PeopleAgedFemaleHumansMaleMiddle AgedQuality of LifeSingle-Blind Methodactivity engagementcaregivingdementia caremental health

Identifiers

PMID41139689
PMCPMC12554832

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.