Evidence map›Paper›PMID 41139571›Full record

ReviewTrends in parasitology2025

Resolving tissue and cellular functions of parasitic nematodes.

Paul M Airs, María A Duque-Correa

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul M AirsCambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
María A Duque-CorreaCambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK. Electronic address: mad75@cam.ac.uk.

Funding

Wellcome Trust 222546
6 · The paper itself

Abstract

Parasitic nematodes have a significant impact on global health as pathogens of humans and animals. Yet, our understanding of parasite physiology and the function of organs critical for intra-host survival is poor. Most knowledge is derived from Caenorhabditis elegans, a free-living nematode that has limited translatability to parasitic species. Here, we discuss opportunities to fill knowledge gaps in fundamental parasite biology through the study of parasite body plans, tissues, and cells in their biological context, using modern imaging, omics, metabolic models, and in vitro culture systems. Resolving the functions of parasite cells and tissues throughout development and inside their hosts is key to discovering new tools to tackle them.

Indexed as

Host-Parasite InteractionsNematodaAnimalsCaenorhabditis elegansHumansanatomyhost–parasite interactionsomicsparasite developmentparasitic nematodestissue function

Identifiers

PMID41139571
PMCPMC7618447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.