Evidence map›Paper›PMID 41139401›Full record

ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2025

Longitudinal assessment of fetal myocardial performance index in normal pregnancy using spectral tissue Doppler.

R Horgan, E Sinkovskaya, E Kalafat, G Saade, A Abuhamad

Abstract read
In one paragraph

Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. How to assess ventricular function by fetal echocardiography: expert guidance from the Fetal Heart Society.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R HorganDepartment of Obstetrics & Gynecology, Macon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School at Old Dominion University, VA, USA.ORCID 0000-0002-2752-4061
E SinkovskayaDepartment of Obstetrics & Gynecology, Macon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School at Old Dominion University, VA, USA.
E KalafatDepartment of Obstetrics & Gynecology, Koc University Hospital, Istanbul, Turkey.ORCID 0000-0003-0658-138X
G SaadeDepartment of Obstetrics & Gynecology, Macon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School at Old Dominion University, VA, USA.
A AbuhamadDepartment of Obstetrics & Gynecology, Macon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School at Old Dominion University, VA, USA.

Funding

Novel Tools for the Noninvasive Evaluation of the Human PlacentaR01HD086313 · NICHD · EASTERN VIRGINIA MEDICAL SCHOOL · PI ABUHAMAD, ALFRED Z, SAADE, GEORGE R. · 2015 to 2018
$2.7M
National Institute of Child Health and Human Development HD 086313-01NICHD NIH HHS R01 HD086313
6 · The paper itself

Abstract

objectiveAlthough spectral tissue Doppler imaging is recognized as the optimal method for assessing the fetal myocardial performance index (MPI), longitudinal reference ranges for fetal MPI measured using spectral tissue Doppler have not been established. Our objective was to use spectral tissue Doppler data to establish gestational-age-specific reference ranges from 12-33 weeks for left and right ventricular fetal MPI.

methodsThis was a prospective longitudinal study of women aged 18-35 years, with a body mass index below 30 kg/m

resultsMedian fetal MPI was determined for the right and left ventricles at 12-13 weeks, 20-21 weeks and 32-33 weeks' gestation in 90 fetuses. Using multilevel regression modeling, weekly reference ranges for each gestational age were created to provide a continuous characterization of normal fetal MPI assessed using spectral tissue Doppler throughout pregnancy. Percentile reference ranges (5

conclusionWe have established gestational-age-specific reference ranges for left and right ventricular fetal MPI using spectral tissue Doppler imaging, thus providing clinicians with an important tool for the early detection of fetal cardiac dysfunction in high-risk pregnancies. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Indexed as

Echocardiography, DopplerFetal HeartUltrasonography, PrenatalAdolescentAdultFemaleGestational AgeHeart VentriclesHumansLongitudinal StudiesPregnancyProspective StudiesReference ValuesYoung Adultfetalmyocardial performance indexreference rangetissue Dopplerultrasound

Identifiers

PMID41139401
PMCPMC12671935

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.