Evidence map›Paper›PMID 41139392›Full record

ArticleJournal of clinical psychology2026

Application of Psychometric Methods in Dimensional Analysis and Integration of Assessment Tools in Early Diagnosis for Autism Spectrum Disorder.

Ilenia Le Donne, Monica Mazza, Margherita Attanasio, Nicole Covone, Maria Paola Greco, Veronica Scurti, Marco Valenti

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Article in Journal of clinical psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ilenia Le DonneDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.ORCID 0000-0002-8157-2240
Monica MazzaDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.
Margherita AttanasioDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.
Nicole CovoneDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.
Maria Paola GrecoDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.
Veronica ScurtiDepartment of Health, Abruzzo Region, Italy.
Marco ValentiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.

Funding

This study received no specific funding for this work.
6 · The paper itself

Abstract

backgroundEarly diagnosis of autism spectrum disorder (ASD) is crucial for timely intervention, and requires reliable and valid screening and diagnostic tools. The Toddler Module of the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), is widely used but its factor structure and applicability in the clinical practice need further investigation.

objectiveThis study aimed to explore the underlying dimensional structure of the ADOS-2 Toddler Module in Italian context, and to examine the association between the identified ASD symptom dimensions and cognitive development, as measured by the Griffiths Mental Development Scales (GMDS).

methodsThe study was conducted in two phases: in Phase 1, Exploratory Graph Analysis (EGA) was used to identify latent dimensions of the ADOS-2 Toddler Module items in a sample of 91 Italian children aged 12-30 months at risk for ASD. In Phase 2, structural equation modeling (SEM) was performed on a subsample of 60 children who completed the GMDS to examine associations between ASD symptom dimensions and cognitive development.

resultsEGA revealed a stable three-factor structure underlying the Toddler Module items. The SEM analysis demonstrated a good model fit and significant associations between ASD symptom dimensions and the Personal-Social subscale of the GMDS.

conclusionsThese findings provide preliminary evidence for a three-dimensional structure of ASD symptoms in very young children and suggest that cognitive development, particularly social-personal skills, is related to early ASD symptomatology. The results have potential implications for refining early diagnostic assessments and guiding clinical practice.

Indexed as

Autism Spectrum DisorderChild DevelopmentPsychiatric Status Rating ScalesPsychometricsChild, PreschoolEarly DiagnosisFemaleHumansInfantItalyMaleADOS‐2assessmentautismexploratory graph analysispsychometrystructural equation model

Identifiers

PMID41139392
PMCPMC12882800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.