Evidence map›Paper›PMID 41139375›Full record

Observational studyInternal and emergency medicine2026

The effect of fascial block on opioid consumption in patients with multiple rib fractures: a retrospective observational study.

Sossio Serra, Domenico Pietro Santonastaso, Giuseppe Romano, Alessandro Riccardi, Francesca Ortu, Vanni Agnoletti, Mario Guarino, Claudia Sara Cimmino, Michele Domenico Spampinato, Michela Cascio and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sossio SerraUOC Pronto Soccorso E Medicina d'Urgenza, Ospedale Ramazzini, 41012, Carpi, Modena, Italy.
Domenico Pietro SantonastasoAnestesia and Intensive Care Unit, Emergency Department, Maurizio Bufalini Hospital, 47521, Cesena, Italy.
Giuseppe RomanoEmergency Department, Maurizio Bufalini Hospital, 47521, Cesena, Italy.
Alessandro RiccardiSC Pronto Soccorso E Medicina d'Urgenza, Ospedale Santa Corona, Pietra Ligure, 17027, Savona, Italy.
Francesca OrtuUO Pronto Soccorso E Medicina d'Urgenza, "Ospedale Degli Infermi", 48018, Faenza, Italy.
Vanni AgnolettiAnestesia and Intensive Care Unit, Emergency Department, Maurizio Bufalini Hospital, 47521, Cesena, Italy.
Mario GuarinoUOC MEU Ospedale CTO-AORN Dei Colli Napoli, 80131, Naples, Italy.
Claudia Sara CimminoUOC MEU Ospedale CTO-AORN Dei Colli Napoli, 80131, Naples, Italy.
Michele Domenico SpampinatoDepartment of Translational Medicine and for Romagna, University of Ferrara, Via A. Moro 8, 44124, Cona, Ferrara (FE), Italy. spmmhl@unife.it.ORCID http://orcid.org/0000-0002-2285-327X
Michela CascioEmergency Department, Maurizio Bufalini Hospital, 47521, Cesena, Italy.
Raffella FrancesconiEmergency Department, Maurizio Bufalini Hospital, 47521, Cesena, Italy.
Fabio De IacoStruttura Complessa Di Medicina Di Emergenza, Urgenza Ospedale Maria Vittoria, ASL Città Di Torino, 10144, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain is a common feature in multiple rib fractures. Opioids are the mainstay of analgesic therapy due to their high efficacy, however, can lead to a reduction in respiratory rate and tidal volume, sedation and respiratory failure. Fascial blocks can provide safe, adequate analgesia with only local effects. This study aims to investigate the effect of fascial block on the reduction of total opioid consumption. A retrospective observational study, conducted in the emergency medicine unit (EMU), including all adult, opioid-naïve patients admitted between January 2022 and August 2024 with post-traumatic blunt chest trauma. 103 patients, 26 (27.9%) women, with a median age of 62 years (IQR 56-76), a median Thoracic Trauma Severity Score (TTSS) of 8 (IQR 7-9), a median pain score of 8 on the 0-10 Numeric ranking scale, and 66 patients (60.2%) underwent fascial block. Median total opioid consumption was 92 morphine milligram equivalents (IQR 61.5-140), significantly lower in patients undergoing fascial block (71 (IQR 60-101) vs. 150 (110-210), p < 0.001), despite higher pain on admission (8 (IQR 7-9) vs. 6 (IQR 5-7), p < 0.01), with better pain control and no differences in total length of stay, TTSS or number of rib fractures. This study shows that fascial blocks in patients admitted to the EMU for post-traumatic pain due to multiple rib fractures are associated with a significant reduction in overall opioid consumption and no specific complication, supporting the use of a multimodal approach for better pain control.

Indexed as

Analgesics, OpioidNerve BlockPain ManagementRib FracturesAgedFemaleHumansMaleMiddle AgedPain MeasurementRetrospective StudiesAnalgesics, OpioidChest traumaEmergency medicineFascial blockMultiple rib fracturesOpioid consumptionPain management

Identifiers

PMID41139375
PMCPMC13582408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.