Evidence map›Paper›PMID 41139371›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Clinical characteristics and risk factors of mortality in patients with candidemia: a four-year retrospective study.

Shuang Li, Lili Yang, Xiaoyan Feng, Xi Peng, Junmei Zhang, Min Liu, Ke Li

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shuang LiDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China.
Lili YangDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China.
Xiaoyan FengDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China.
Xi PengDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China.
Junmei ZhangDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China.
Min LiuDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China.
Ke LiDepartment of Clinical Laboratory Medicine, the Third People's Hospital of Chengdu, the Affiliated Hospital of Southwest Jiaotong University, NO.82 Qinglong Street, Qingyang District, Sichuan, Chengdu, 610031, China. cd600800@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough candidemia has been reported globally, little is known about the differences in candidemia episodes between ICU and regular wards or the correlation between serum biomarkers and mortality from candidemia in medium and small cities. PATIENTS AND

methodsWe conducted a retrospective study of the risk factors and clinical outcomes of hospitalized patients with candidemia from 2021 to 2024 in southwest China. A multivariate logistic regression model was performed to investigate several potential risk factors for mortality.

resultsWe collected 152 non-duplicate candidemia isolates during the study period. Candida albicans was the leading species causing candidemia (33.6%), and 96.7% of these isolates were susceptible to amphotericin B. Compared with regular patients, patients admitted to ICU were more frequently subjected to severe clinical presentations, extensive invasive procedures, and heavy exposure to antibiotics. In addition, the mortality in ICU was significantly higher than that in regular wards. Multivariable analysis revealed that 30-day readmission, mechanical ventilation, and ICU admission were independent factors associated with 30-day mortality. Moreover, we observed that high levels of PCT, BDG, and IL-6, as well as low PLT counts were also associated with mortality from candidemia.

conclusionsA better understanding of the specific risk factors across ICU wards could facilitate the identification of high-risk candidates for early antifungal therapy, thereby improving the outcomes for critically ill patients with candidemia.

Indexed as

CandidaCandidemiaAdultAgedAged, 80 and overAntifungal AgentsChinaFemaleHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesRisk FactorsAntifungal AgentsCandidemiaICUMortalityRisk factors

Identifiers

PMID41139371
PMCPMC12987824

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