Trial reportInternational urology and nephrology2026
Comparison of retrograde ıntrarenal surgery performed with thulium fiber laser lithotripsy and percutaneous nephrolithotomy in the treatment of 20-30 mm kidney stones in adults: a randomized prospective study.
Trial report in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Complications of thulium fiber laser lithotripsy: a systematic review and meta-analysis by the EAU-YAU endourology and urolithiasis working group.World journal of urology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to contribute to the literature by investigating whether Retrograde Intrarenal Surgery (RIRC) performed with Thulium Fiber Laser Lithotripsy (TFLLT) can be an alternative to Percutaneous Nephrolithotomy (PNL), which is still considered the gold standard, for the treatment of kidney stones measuring 20-30 mm, a more invasive procedure. Between April 2022 and June 2024, patients with a single kidney stone (Guy stone score 1) located in the renal pelvis, lower pole, or middle pole, measuring between 20-30 mm, were randomized at the Urology Clinic of Atatürk University Research Hospital. A total of 86 patients were included in the study. 44 patients (51.1%) underwent RIRS with TFLLT, and 42 patients (48.8%) underwent PNL. The mean stone size was 24.7 ± 1.8 mm in the RIRS group and 24.8 ± 1.7 mm in the PNL group. There was no statistically significant difference in demographics and stone characteristics between the two groups (p0.05). Stone-free rates were statistically similar between the two groups (p=0.714). The mean operative time was longer in the RIRS group, while the mean hemoglobin decrease and hospital stay were longer in the PNL group (p0.001). No statistically significant difference was found in postoperative complications between the groups (p=0.806). In the treatment of kidney stones measuring 20-30 mm, RIRC with TFLLT provides advantages over PNL, including lower blood loss, shorter hospitalization, lower fluoroscopy time, less postoperative pain, and lower analgesic consumption. With similar complication and stone-free rates, thulium fiber laser lithotripsy (TFLLT) performed via retrograde intrarenal surgery (RIRS) may have the potential to be a safe and effective alternative to percutaneous nephrolithotomy (PNL). Further studies with larger patient series will contribute to the literature.
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Registered trials
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