Evidence map›Paper›PMID 41139239›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2025

Analysis of the Predictive Effect of Cardiac Color Doppler Ultrasound Combined With Carotid Ultrasound on Major Adverse Cardiac Events Following Percutaneous Coronary Intervention.

Jun Xue, Di Wu, Yudong Fan, Miaomiao Zhang, Xu Wang

RetractedAbstract readRetracted Publication
In one paragraph

Article in Echocardiography (Mount Kisco, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jun XueDepartment of Cardiology, Emergency General Hospital, Chaoyang District, Beijing, China.
Di WuDepartment of Cardiology, Emergency General Hospital, Chaoyang District, Beijing, China.ORCID 0009-0006-6105-9331
Yudong FanDepartment of Cardiology, Emergency General Hospital, Chaoyang District, Beijing, China.
Miaomiao ZhangDepartment of Cardiology, Emergency General Hospital, Chaoyang District, Beijing, China.
Xu WangDepartment of Imaging, Emergency General Hospital, Chaoyang District, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study sought to investigate the predictive effect of combining cardiac color Doppler ultrasound and carotid ultrasound for major adverse cardiac events (MACE) following percutaneous coronary intervention (PCI).

methodsA retrospective analysis was conducted on 475 coronary heart disease (CHD) patients who underwent PCI between May 2021 and April 2024. Cardiac ultrasound parameters (left atrial diameter [LAD], left ventricular diameter in diastole [LVDd]) and carotid ultrasound metrics (plaque score, intima-media thickness [IMT], total plaque area [TPA], and gray scale median [GSM]) were collected within 48 h post-PCI. Patients were monitored for a 12-month period to record MACE incidence. After 12 months of follow-up, patients were assigned to a Without MACE group (n = 324) and a With MACE group (n = 151). Correlation and multivariate logistic regression analyses were conducted to identify predictors, and receiver operating characteristic (ROC) curves evaluated predictive accuracy.

resultsAmong 151 patients (31.8%) who experienced MACE, significant predictors included diabetes requiring medication (OR = 1.80, p = 0.039), prior myocardial infarction (OR = 1.93, p = 0.009), elevated discharge heart rate (OR = 1.10, p = 0.013), Charlson Comorbidity Index (OR = 1.60, p = 0.002), maximum left ventricular thickness (OR = 1.181, p = 0.003), higher Tei index (OR = 1.386, p = 0.001), plaque score (OR = 5.032, p = 0.001), carotid IMT (OR = 2.216, p = 0.002), and TPA (OR = 1.039, p = 0.016). Protective factors included beta-blocker use (OR = 0.468, p = 0.027), higher LVEF (OR = 0.957, p = 0.009), and higher GSM (OR = 0.894, p = 0.045). The combined ultrasound model achieved an AUC of 0.833, demonstrating robust predictive accuracy.

conclusionCardiac color Doppler ultrasound combined with carotid ultrasound effectively predicts post-PCI MACE by integrating cardiac function and atherosclerotic plaque characteristics. These non-invasive imaging tools offer a valuable framework for early risk assessment and personalized treatment strategies in CHD patients following PCI.

Indexed as

Carotid ArteriesEchocardiography, Doppler, ColorPercutaneous Coronary InterventionPostoperative ComplicationsAgedCarotid Intima-Media ThicknessFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesUltrasonography, Carotid Arteriescardiac color doppler ultrasoundcarotid ultrasoundmajor adverse cardiac eventspercutaneous coronary interventionrisk prediction

Identifiers

PMID41139239
PMCPMC12554012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.