ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025
Subtotal tumor resection as a predictor of post-resection hydrocephalus in pediatric patients with posterior fossa tumors.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Predicting late-onset hydrocephalus in pediatric medulloblastoma: from static anatomy to dynamic biological assessment.Neurosurgical review · 2026Article
- Letter to the Editor regarding "Subtotal tumor resection as a predictor of post-resection hydrocephalus in pediatric patients with posterior fossa tumors".Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
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Abstract
objectivePediatric posterior fossa tumor (PFT) resection is frequently complicated by postoperative hydrocephalus. Previous hydrocephalus risk stratification tools demonstrate limited performance in external validation and do not account for important intra- and post-operative variables. We aimed to evaluate additional risk factors for post-resection hydrocephalus to improve risk-stratification.
methodsWe conducted a retrospective analysis of pediatric patients who underwent resection of primary PFT's at our institution (January 2016-June 2024). We collected perioperative variables thought to influence hydrocephalus risk. The primary outcome was permanent CSF diversion within 6 months after resection. We used univariable and multivariable logistic regression with bidirectional stepwise selection to identify predictors of post-resection hydrocephalus.
resultsA total of 112 patients were included. We identified age < 5 years, moderate/severe hydrocephalus, and subtotal resection (STR; ≥ 1.5 cm
conclusionsThese findings suggest STR is associated with increased risk of persistent hydrocephalus and emphasize careful intraoperative decision-making when pursuing incomplete resection. Future multicenter studies will be necessary to validate this framework and to further elucidate how STR, in conjunction with age and hydrocephalus severity, can be leveraged to optimize treatment strategies in diverse healthcare settings.
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