Evidence map›Paper›PMID 41139141›Full record

ReviewBiodegradation2025

Anaerobic reactors for hospital wastewater treatment: a critical review of microbial communities in the antibiotic biodegradation and ecotoxicological impacts.

Mateus Cottorello-Fonsêca, Gleyson B Castro, Juliano J Corbi, Marcelo Zaiat

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biodegradation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mateus Cottorello-FonsêcaDepartment of Hydraulic and Sanitation, Laboratory of Biological Processes, São Carlos School of Engineering, University of São Paulo, 1100 João Dagnone Ave., Santa Angelina, São Carlos, São Paulo, 13563-120, Brazil. mateuscottorello@gmail.com.ORCID 0000-0002-8075-0092
Gleyson B CastroDepartment of Hydraulic and Sanitation, Laboratory of Ecotoxicology and Applied Ecology, São Carlos School of Engineering, University of São Paulo, 1100 João Dagnone Ave., Santa Angelina, São Carlos, São Paulo, 13563-120, Brazil.ORCID 0000-0001-5706-904X
Juliano J CorbiDepartment of Hydraulic and Sanitation, Laboratory of Ecotoxicology and Applied Ecology, São Carlos School of Engineering, University of São Paulo, 1100 João Dagnone Ave., Santa Angelina, São Carlos, São Paulo, 13563-120, Brazil.ORCID 0000-0003-0249-9370
Marcelo ZaiatDepartment of Hydraulic and Sanitation, Laboratory of Biological Processes, São Carlos School of Engineering, University of São Paulo, 1100 João Dagnone Ave., Santa Angelina, São Carlos, São Paulo, 13563-120, Brazil.ORCID 0000-0001-7336-9093

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001ERA-NET AquaticPollutants Joint Transnational Call 869178EU and the State Research Agency (AEI) PCI2022-121990Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/15087-8, 2020/11042-0 and 2022/12048-7
6 · The paper itself

Abstract

Global scientific literature has extensively documented the overuse of antibiotics, the proliferation of antibiotic-resistant bacteria, and the toxic effects on aquatic fauna from hospital wastewater exposure, highlighting the need for effective antibiotics treatment methodologies. Anaerobic biodegradation has been recognized as an effective method for removing antibiotics and other pharmaceuticals from hospital wastewater, demonstrating the ability to degrade various antibiotic classes. This review critically examines the environmental fate of the antibiotics classes fluoroquinolones, sulfonamides, and diaminopyrimidines in hospital wastewater, emphasizing anaerobic biodegradation as an effective technology and the significance of the microbial community in this process. Furthermore, it examines ecotoxicological impacts across diverse species. The inappropriate disposal of inadequately treated hospital effluent into the environment disseminates antibiotics into freshwater, resulting in sublethal effects on aquatic fauna. The current research gap underscores the promise of anaerobic technologies, coupled with the toxicity assessment of treated effluents containing antibiotic mixtures, to improve comprehension of the environmental fate and effects of these antibiotic classes on aquatic vertebrate and invertebrate species.

Indexed as

Anti-Bacterial AgentsBioreactorsWaste Disposal, FluidWastewaterWater Pollutants, ChemicalAnaerobiosisAnimalsBacteriaBiodegradation, EnvironmentalEcotoxicologyHospitalsAnti-Bacterial AgentsWastewaterWater Pollutants, ChemicalAnaerobic reactorsDiaminopyrimidinesEcotoxicityFluoroquinolonesMicrobial communitySulfonamides

Identifiers

PMID41139141

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.