Evidence map›Paper›PMID 41139130›Full record

ArticleMacromolecular rapid communications2026

Poly(O-Propargyl-N-Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s.

Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil-Bouzas, Andrey Romanyuk, Ivan Torreiro-Leon, Ana Rey-Rico, Paco Fernandez-Trillo

Abstract read
In one paragraph

Article in Macromolecular rapid communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tom LeighSchool of Chemistry, University of Birmingham, Birmingham, UK.
Greta BellioBioNanoChem Lab, Centro Interdisciplinar de Química e Bioloxía - CICA, Universidade Da Coruña, A Coruña, Spain.ORCID https://orcid.org/0009-0007-1840-0300
Daniel CrisanSchool of Chemistry, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0001-6938-3765
Amit DebSchool of Chemistry, University of Birmingham, Birmingham, UK.
Alba Ramil-BouzasBioNanoChem Lab, Centro Interdisciplinar de Química e Bioloxía - CICA, Universidade Da Coruña, A Coruña, Spain.ORCID https://orcid.org/0009-0000-2736-9228
Andrey RomanyukSchool of Chemistry, University of Birmingham, Birmingham, UK.
Ivan Torreiro-LeonBioNanoChem Lab, Centro Interdisciplinar de Química e Bioloxía - CICA, Universidade Da Coruña, A Coruña, Spain.ORCID https://orcid.org/0009-0005-3128-0695
Ana Rey-RicoG-Cel, Centro Interdisciplinar de Química e Bioloxía - CICA, Universidade Da Coruña, A Coruña, Spain.ORCID https://orcid.org/0000-0003-1682-498X
Paco Fernandez-TrilloSchool of Chemistry, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-6680-5683

Funding

Engineering and Physical Sciences Research Council EP/L016346/1HORIZON EUROPE European Innovation Council 795082'la Caixa' Foundation CI22-00167Leverhulme Trust RPG-2019-382Ministerio de Ciencia e Innovación PID2021-128461OB-I00Ministerio de Ciencia, Innovación y Universidades A.R.-B. PRE2022-104070Ministerio de Ciencia, Innovación y Universidades A.R.-R. RYC2018-025617-IMinisterio de Educación, Cultura y Deporte BG20/00213Xunta de Galicia ED431B 2023/60Xunta de Galicia ED431F 2021/10
6 · The paper itself

Abstract

Synthetic polymers are widely used in biomedical applications, yet most lack defined secondary structures common in nature, such as helices or β-sheets. In particular, dynamic helical polymers such as poly(acetylene)s have been rarely explored in this field. Here, we report the preparation of a new reactive poly(acetylene), poly(O-propargyl-N-amino carbamate) (P1), as a platform for the preparation of functional poly(acetylene)s in water. P1 was prepared from readily available starting materials through Rh-catalyzed polymerization and acid-mediated deprotection.

Indexed as

Biocompatible MaterialsCarbamatesPolyacetylene PolymerPolymersHumansMolecular StructurePolymerizationBiocompatible MaterialsCarbamatesPolyacetylene PolymerPolymersbiocompatible polymerspoly(acetylene)spost‐polymerization modification

Identifiers

PMID41139130
PMCPMC13384799

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.