Evidence map›Paper›PMID 41139045›Full record

Trial reportJournal of pain and symptom management2026

Peaceful Acceptance of Illness Among Older Adults With Advanced Cancer: A Randomized Clinical Trial.

Sule Yilmaz, Elizabeth Gilbride, Sofiia Hryniv, William Consagra, Supriya G Mohile, Eva Culakova, Beverly Canin, Arul Malhotra, Rachael Tylock, Judith O Hopkins and 6 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pain and symptom management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02107443 (Improving Communication for Cancer Treatment), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02107443 nacompletednot on this map

Improving Communication for Cancer Treatment: Addressing Concerns of Older Cancer Patients and Caregivers

TypeinterventionalSponsorSupriya MohileRan2014 to 2020Enrolled546ConditionsAdult Solid Neoplasm, LymphomaArmsGeriatric Assessment Summary, Geriatric Assessment Targeted Recommendations, Geriatric Assessment (GA)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sule YilmazDepartment of Medicine (S.Y., M.L.), University of Rochester Medical Center, Rochester, New York, USA.
Elizabeth GilbrideDivision of Hematology/Oncology (E.G., S.H., S.G.M., R.T., A.M., K.P.L.), Department of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
Sofiia HrynivDivision of Hematology/Oncology (E.G., S.H., S.G.M., R.T., A.M., K.P.L.), Department of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
William ConsagraDepartment of Statistics (W.C.), University of South Carolina, Columbia, South Carolina, USA.
Supriya G MohileDivision of Hematology/Oncology (E.G., S.H., S.G.M., R.T., A.M., K.P.L.), Department of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
Eva CulakovaUniversity of Rochester Medical Center Alumni (E.C.), Rochester, New York, USA.
Beverly CaninSCOREboard (B.C.), University of Rochester, Rochester, New York, USA.
Arul MalhotraUniversity of Rochester School of Medicine and Dentistry (A.M.), Rochester, New York, USA.
Rachael TylockDivision of Hematology/Oncology (E.G., S.H., S.G.M., R.T., A.M., K.P.L.), Department of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
Judith O HopkinsSoutheast Clinical Oncology Research Consortium (SCOR) National Cancer Institute Community Oncology Research Program (NCORP)/Novant Health Cancer Institute (J.O.H.), Kernersville, North Carolina, USA.
Jane Jijun LiuHeartland Cancer Research NCORP (HEARTLAND) (J.J.L.), Peoria, Illinois, USA.
Jamil KhatriDelaware/Christiana Care NCORP (CHRISTIANA) (J.K.), Middletown, Delaware, USA.
Marissa LoCastroDepartment of Medicine (S.Y., M.L.), University of Rochester Medical Center, Rochester, New York, USA.
Maya AnandDepartment of Epidemiology (M.A.), University of Rochester Medical Center, Rochester, New York, USA.
Allison MagnusonDivision of Hematology/Oncology (E.G., S.H., S.G.M., R.T., A.M., K.P.L.), Department of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
Kah Poh LohDivision of Hematology/Oncology (E.G., S.H., S.G.M., R.T., A.M., K.P.L.), Department of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA. Electronic address: kahpoh_loh@urmc.rochester.edu.

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

contextPeaceful acceptance of illness is associated with lower psychological distress and increased engagement in advance care planning among adults with advanced cancer. Limited data exist on factors influencing illness acceptance in older adults.

objectivesTo examine patient, caregiver, and oncologist characteristics associated with peaceful acceptance of illness in older adults with advanced cancer.

methodsA secondary analysis of a cluster-randomized trial evaluating the impact of geriatric assessment (GA) on cancer care in community oncology practices (NCT02107443). Participants included 333 patient-caregiver dyads. Patients were aged ≥70 years, had incurable stage III/IV solid tumors or lymphoma, and ≥1 GA impairment. Peaceful acceptance of illness was measured using the 5-item PEACE scale (range 5-20; higher scores indicate greater acceptance). Multivariable linear regression examined associations between PEACE scores and patient (e.g., GA impairments), caregiver (e.g., education), and oncologist factors (e.g., confidence).

resultsThe mean (standard deviation, SD) age was 76.8 (5.4) years for patients and 66.6 (12.1) years for caregivers. Common cancers included lung (27%), gastrointestinal (26%), and genitourinary (16%). Mean (SD) PEACE score was 17.4 (2.5), indicating high illness acceptance. Lower acceptance was associated with psychological impairment (b = -0.92; 95% CI, -1.56 to -0.29), shorter patient-estimated life expectancy (b = -1.06; 95% CI, -2.06 to -0.06), and caregiver education ≤high school (b = 0.90; 95% CI, 0.32-1.49). No oncologist factors were significantly associated.

conclusionPatient psychological health, perceived prognosis, and caregiver education were linked to PEACE. Triadic interventions addressing these factors may enhance end-of-life care for older adults with advanced cancer.

Indexed as

NeoplasmsAgedAged, 80 and overCaregiversFemaleGeriatric AssessmentHumansMaleAdvanced cancerCaregiversIllness acceptanceOlder adultsOncologistsPeace

Identifiers

PMID41139045
PMCPMC12967279

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.