ArticleChemistry & biodiversity2026
Phytochemical Profiling, Bioactivity Evaluation and In Silico Insights Onto Goniothalamus simonsii Hook. f. Thoms.: An Endangered Medicinal Plant.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Goniothalamus simonsii Hook. f. Thoms., an endangered medicinal plant is endemic to the state of Meghalaya, India. Its wide use in traditional medicine in Meghalaya for treating gastrointestinal complications, throat irritation and typhoid fever, is not matched by scientific reports on its pharmacological attributes. The present investigation evaluated the phytochemical constituents by GC-MS analysis; while bioactivities including antioxidant, antimicrobial and cytotoxicity were assessed by DPPH, agar-well diffusion and MTT methods, respectively. The leaf extract showed elevated content of phenolics (154.76 ± 7.98 mg GAE/g) and flavonoids (55.91 ± 3.05 mg QE/g). GC-MS analysis identified compounds included cis-vaccenic acid, kavain, 3-methoxy-2-(quinoxalin-6-yliminomethyl), spathulenol, aziridine, stigmasterol, n-hexadecanoic acid, cholest-4-en-3-one, coniferyl alcohol and so forth. Leaf extract displayed IC
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