Evidence map›Paper›PMID 41138218›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2025

Collagen VIII: a new guardian of endothelial cell identity in atherosclerosis.

Ishita Kathuria, Ravi Varma Aithabathula, Bhupesh Singla

Abstract readComment
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ishita KathuriaDepartment of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, Tennessee, United States.
Ravi Varma AithabathulaDepartment of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, Tennessee, United States.
Bhupesh SinglaDepartment of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, Tennessee, United States.ORCID 0000-0003-2752-6849

Funding

RSPO2-LGR4 signaling in atherosclerosisR01HL172809 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Bhupesh Singla · 2025 to 2026
$1.1M
Regulation of Lymphangiogenesis by Thrombospondin 1R00HL146954 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SINGLA, BHUPESH · 2022 to 2024
$739k
Regulation of Lymphangiogenesis by Thrombospondin 1K99HL146954 · NHLBI · AUGUSTA UNIVERSITY · PI SINGLA, BHUPESH · 2020 to 2021
$232k
American Heart Association (AHA) 25PRE1374518HHS | National Institutes of Health (NIH) K99HL14695HHS | National Institutes of Health (NIH) R00HL146954HHS | National Institutes of Health (NIH) R01HL172809NHLBI NIH HHS K99 HL146954NHLBI NIH HHS R00 HL146954NHLBI NIH HHS R01 HL172809UT | Health Science Center, University of Tennessee (UTHSC) College of Pharmacy Startup and Seed Research Grant
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

collagen type VIIIendothelial-to-mesenchymal transitiontumor necrosis factor-α

Identifiers

PMID41138218
PMCPMC12594533

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.