Evidence map›Paper›PMID 41138041›Full record

ReviewMycopathologia2025

Antifungal Prescription and Stewardship in Pediatrics.

Paschalis Evangelidis, Elisavet Chorafa, Maria Kourti, Elias Pilianidis, Elias Iosifidis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paschalis EvangelidisPediatric Infectious Disease Unit, 3rd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki and Hippokration General Hospital, Thessaloniki, Greece.
Elisavet ChorafaPediatric Infectious Disease Unit, 3rd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki and Hippokration General Hospital, Thessaloniki, Greece.
Maria KourtiPediatric Infectious Disease Unit, 3rd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki and Hippokration General Hospital, Thessaloniki, Greece.
Elias PilianidisPediatric Infectious Disease Unit, 3rd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki and Hippokration General Hospital, Thessaloniki, Greece.
Elias IosifidisPediatric Infectious Disease Unit, 3rd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki and Hippokration General Hospital, Thessaloniki, Greece. iosifidish@gmail.com.ORCID http://orcid.org/0000-0001-9881-451X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal infections constitute a major cause of morbidity and mortality in children, affecting mainly those with malignancies and immunodeficiencies (primary or secondary), who receive solid or hematopoietic stem cell transplantation, and those in neonatal or pediatric intensive care units. Overuse and inappropriate prescription of antifungal (AF) agents have been reported in pediatrics, leading not only to an increase in adverse events and toxicities but also to the development of AF resistance. AF stewardship practices as part of broader antimicrobial stewardship programs are crucial for improving outcomes and reducing AF overuse and associated costs. This review has two main objectives: to summarize the published data on prescription patterns of AF agents in pediatrics and to describe the current state of pediatric AF stewardship programs worldwide, providing suggestions for their implementation. Given the significant burden of invasive fungal infections in vulnerable pediatric populations, identification of actions to improve AF stewardship practices in real-life clinical settings is essential.

Indexed as

Antifungal AgentsAntimicrobial StewardshipDrug PrescriptionsInvasive Fungal InfectionsPediatricsChildHumansAntifungal AgentsAntifungalInvasive fungal diseaseNeonatalPediatricsPrescriptionStewardship

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.