Observational studyJapanese journal of ophthalmology2026
Evaluation of 60 months long-term results of accelerated corneal cross-linking treatment in pediatric keratoconus patients with new progression indices.
Observational study in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo investigate the long-term efficacy of accelerated corneal cross-linking (CXL) with Belin ABCD progression display in pediatric keratoconus patients. STUDY
designRetrospective observational cohort study.
methodsThis retrospective study included 40 eyes of 40 pediatric keratoconus patients who underwent accelerated CXL (10 min/9 mW/cm
resultsIimprovements in visual acuity, gauged by regression in anterior curvature, progression in posterior curvature and corneal thickness, were observed using the ABCD progression display at the end of the 60 months follow-up. Significant improvements in K1, K2, maximum keratometry, anterior elevation and anterior asphericity values and significant worsening in the posterior elevation values were observed with topographical parameters. Significant thinning in pachymetric indices was observed with Belin/Ambrósio enhanced ectasia display.
conclusionAccelerated CXL is efficient in pediatric keratoconus patients in halting the disease progression. Visual and keratometric stabilization continued over a long follow-up period of 60 months. Belin ectasia progression display may be very helpful in the longitudinal follow-up of pediatric keratoconus patients after CXL.
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