Evidence map›Paper›PMID 41137994›Full record

ArticleJournal of assisted reproduction and genetics2025

Parental dietary patterns and assisted reproductive technology outcomes including embryo morphokinetics: rotterdam periconception cohort.

Batoul Hojeij, Sam Schoenmakers, Lenie van Rossem, Sten Willemsen, Esther Baart, Melek Rousian, Régine P M Steegers-Theunissen

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Batoul HojeijDepartment of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.
Sam SchoenmakersDepartment of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.
Lenie van RossemDepartment of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.
Sten WillemsenDepartment of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.
Esther BaartDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.
Melek RousianDepartment of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.
Régine P M Steegers-TheunissenDepartment of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands. r.steegers@erasmusmc.nl.ORCID http://orcid.org/0000-0002-4353-5756

Funding

European Union's Horizon 2020 research and innovation programme 812660
6 · The paper itself

Abstract

purposeThis exploratory study investigated the associations between dietary patterns of subfertile couples and assisted reproductive technology (ART) outcomes, including preimplantation embryo morphokinetics.

methodsFrom the ongoing Rotterdam periconception cohort, we included 149 women and 126 men attending a fertility outpatient clinic for ART treatment. Dietary intake was assessed using a validated self-reported food frequency questionnaire with implausible dietary reporters excluded. We identified four dietary patterns in women and men separately. Embryo morphokinetics included the timing of each division from two to eight cell stage (t2 to t8) and to blastocyst formation, second and third cell cycle and synchrony, and the Known Implantation Data score on embryonic day 3 (KIDscore D3). ART outcomes included the fertilization rate, embryo yield, clinical pregnancy, and live birth.

resultsMaternal adherence to the "Healthy" pattern was associated with shorter S2 (β

conclusionsThis study showed small but consistent associations between parental diet and preimplantation embryo morphokinetics, with no overall effects on ART outcomes.

Indexed as

BlastocystDietEmbryonic DevelopmentReproductive Techniques, AssistedAdultCohort StudiesEmbryo ImplantationEmbryo TransferFemaleFertilization in VitroHumansLive BirthMalePregnancyPregnancy RateAssisted reproductive technologyDietEmbryo developmentFertilityTime-lapse imaging

Identifiers

PMID41137994
PMCPMC12705913

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.