Evidence map›Paper›PMID 41137914›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Risk factors associated with anticipatory nausea and vomiting in children receiving chemotherapy: a cross-sectional study.

Jiajie Fan, Ying Zhou, Guannan Bai, Xiaoyi Chu, Jiajin Di, Luyan Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiajie FanDepartment of Intensive Care, Children's Hospital Affiliated to Zhejiang University School of Medicine, National Clinical Research Center for Children's Health, Hangzhou, 310052, Zhejiang, China.
Ying ZhouDepartment of Neurosurgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, Zhejiang, People's Republic of China.
Guannan BaiDepartment of Child Health Care, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, Zhejiang, People's Republic of China.
Xiaoyi ChuDepartment of Neurosurgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, Zhejiang, People's Republic of China.
Jiajin DiDepartment of Neurosurgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, Zhejiang, People's Republic of China.
Luyan YuDepartment of Neurosurgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, Zhejiang, People's Republic of China. jiajiefan@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAnticipatory nausea and vomiting can impose a significant physical and psychological burden on children and their families, but the risk factors for the development of anticipatory nausea and vomiting in children receiving chemotherapy are unclear. The aim of this study was to investigate the risk factors for anticipatory nausea and vomiting in children receiving chemotherapy, to provide a basis for medical personnel to formulate a pre-chemotherapy anti-vomiting program, to reduce the discomfort experience of children undergoing chemotherapy, and to improve the quality of life.

methodsA prospective cohort study using the Baxter Facial Scale and the Department of Health and Human Services Vomiting Severity was conducted to collect risk factors for anticipatory nausea and vomiting in children receiving chemotherapy at a tertiary-level children's hospital in China in 2022, and logistic regression analysis was performed.

findingsOf the 378 children with chemotherapy, 155 (41.01%) had anticipatory nausea and 40 (10.58%) had anticipatory vomiting. Logistic regression analysis showed that negative emotions and concomitant discomfort are independent risk factors for anticipatory nausea in children undergoing chemotherapy (P < 0.05); negative emotions, concomitant discomfort, and history of CINV are independent risk factors for anticipatory vomiting in children undergoing chemotherapy(P < 0.05).

Indexed as

Antineoplastic AgentsNauseaNeoplasmsVomitingVomiting, AnticipatoryAdolescentChildChild, PreschoolChinaCross-Sectional StudiesFemaleHumansInfantLogistic ModelsMaleProspective StudiesAntineoplastic AgentsAnticipated nauseaAnticipated vomitingChemotherapyChildhood tumors

Identifiers

PMID41137914
PMCPMC12553590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.