Evidence map›Paper›PMID 41137880›Full record

ArticleChild psychiatry and human development2025

Maternal Trauma history, Maternal Mental health, and Child Behavior: A Prospective Study of mother-child Dyads in Lima, Peru.

Mathilda Regan, Elizabeth Levey, Archana Basu, Yinxian Chen, Sixto E Sanchez, Marta B Rondon, Aisha K Yousafzai, Karestan Koenen, Shekhar Saxena, Christopher R Sudfeld and 2 more

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Article in Child psychiatry and human development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Mathilda ReganDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Elizabeth LeveyHarvard Medical School, Boston, MA, USA. elevey@mgb.org.
Archana BasuDivision of Child and Adolescent Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Yinxian ChenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Sixto E SanchezInstituto de Investigaciòn, Facultad de Medicina, Universidad San Martin de Porres, Lima, Peru.
Marta B RondonDepartment of Psychiatry, Instituto Nacional Materno Perinatal, Lima, Peru.
Aisha K YousafzaiDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Karestan KoenenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Shekhar SaxenaDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Christopher R SudfeldDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Henning TiemeierDepartment of Social and Behavioral Science, Harvard T.H. Chan School of Public Health , Boston, MA, USA.
Bizu GelayeDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

Intergenerational impact of maternal trauma history on preschoolers' behavioral health outcomes: Assessing links with caregiving sensitivity and DNA methylationR01HD102342 · NICHD · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI BASU, ARCHANA · 2020 to 2024
$3.0M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD102342Intramural NIH HHS Z99 DA999999Intramural NIH HHS Z99 HD999999Intramural NIH HHS Z99 HL999999Intramural NIH HHS Z99 MH999999Intramural NIH HHS Z99 OD999999NICHD NIH HHS R01 HD102342
6 · The paper itself

Abstract

This study investigates the association between maternal trauma history (lifetime exposure to physical and sexual violence), maternal mental health and child behavior. Pregnant women attending the Instituto Nacional Materno Perinatal (INMP) in Lima, Peru, were recruited to join the study beginning in February 2012. Maternal trauma history and prenatal mental health were assessed at 16-weeks gestation and mothers completed the Child Behavior Checklist when children were four years old. We used causal mediation analysis to examine the association between maternal trauma history and child behavior. This study population included 631 mother-child dyads; 74% of mothers reported one or more lifetime episodes of intimate partner violence (IPV). We found that 32% of the association between maternal lifetime exposure to IPV and child internalizing behavior was mediated by prenatal anxiety. Our findings suggest that prevention and treatment of perinatal IPV and mental health disorders should be prioritized.

Indexed as

AnxietyChild behaviorDepressionMaternal mental healthPTSD

Identifiers

PMID41137880
PMCPMC12854261

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