Evidence map›Paper›PMID 41137829›Full record

ArticleJACC. Case reports2025

The Role of Anticoagulants After Left Atrial Appendage Occlusion.

Maria Segarra-Queralt, Marc Molla, Manal Barrouhou, Andy L Olivares, Carlos Albors, Gabriel Bernardino, Ander Regueiro, Jordi Mill, Òscar Càmara, Xavier Freixa

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Segarra-QueraltDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Marc MollaDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Manal BarrouhouDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Andy L OlivaresDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Carlos AlborsDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Gabriel BernardinoDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Ander RegueiroDepartment of Cardiology, Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain.
Jordi MillDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Òscar CàmaraDepartment of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Xavier FreixaDepartment of Cardiology, Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain. Electronic address: freixa@clinic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft atrial appendage occlusion prevents thromboembolic events in atrial fibrillation patients with bleeding risk, but device-related thrombosis (DRT) remains a challenge. CASE SUMMARY: A 78-year-old man with atrial fibrillation (CHA DISCUSSION: Pulmonary ridge coverage and low-dose direct oral anticoagulants have emerged as effective strategies to reduce DRT. This case links both mechanisms, showing recurrence due to incomplete ridge coverage and antithrombotic decision. TAKE-HOME MESSAGES: Our high-fidelity model offers mechanistic insight about antithrombotic therapy, which cannot be assessed with flow-based simulations alone. The results presented provide proof-of-concept evidence of the model's capabilities.

Indexed as

anticoagulantsatrial fibrillationLAACLAAOlow-dose DOACpulmonary ridge

Identifiers

PMID41137829
PMCPMC12861666

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.