Evidence map›Paper›PMID 41137680›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Influence of recent randomized MeVO trials on current practice patterns and future role of MeVO thrombectomy.

Salome Lou Bosshart, Yu Zhou, Alexander Stebner, Nima Kashani, Mayank Goyal, Michael Hill, Bijoy Menon, Mohammed Almekhlafi, Aravind Ganesh, Nishita Singh and 3 more

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. MeVO: To Treat or Not To Treat? Review of the Latest Evidence.Current neurology and neuroscience reports · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Salome Lou BosshartDepartment of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland.ORCID 0009-0007-7570-8723
Yu ZhouNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Alexander StebnerDepartment of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland.
Nima KashaniDepartment of Radiology, University of Manitoba, Winnipeg, Canada.
Mayank GoyalDepartment of Radiology, Foothills Medical Centre, University of Calgary, Calgary, Canada.
Michael HillDepartment of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, Canada.
Bijoy MenonDepartment of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, Canada.
Mohammed AlmekhlafiDepartment of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, Canada.
Aravind GaneshDepartment of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, Canada.
Nishita SinghDepartment of Neurology, University of Manitoba, Winnipeg, Canada.
Andrew DemchukDepartment of Clinical Neurosciences, Foothills Medical Centre, University of Calgary, Calgary, Canada.
Jianmin LiuNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Johanna Maria OspelDepartment of Radiology, Foothills Medical Centre, University of Calgary, Calgary, Canada.ORCID 0000-0003-0029-6764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionNumerous non-randomized studies suggest the benefit of endovascular thrombectomy (EVT) for medium vessel occlusion (MeVO) stroke, while recent randomized trials showed no benefit. In clinical practice, MeVO management remains heterogeneous. We gauged the current status quo of endovascular MeVO management and physicians' perspectives on future MeVO-EVT trials.MethodsInternational, cross-sectional survey study inquiring about practice patterns before and after publication of the MeVO trials, opinions on the design of second-generation MeVO trials, willingness to enroll in such trials, and personal opinions regarding optimal MeVO treatment strategies. Participants' anonymized responses were summarized using descriptive statistics.ResultsFour hundred fifty-six physicians responded to the survey (308 China, 55 North America, 48 Europe, and 45 other countries). 86/454 (18.9%) respondents reported treating more MeVOs with EVT since the recent MeVO-EVT trials, and 134/454 (29.5%) reported treating fewer. Four-hundred-sixteen of 454 (91.6%) reported that their willingness to enroll patients in a second-generation MeVO-EVT trial increased (282/454 [62.1%]) or remained the same (134/454 [29.5%]) compared to before the recent trial publications. Of 122/454 (26.9%) respondents who participated in a MeVO-EVT trial, 79/121 (65.3%) stated that enrolment bias occurred at their sites. Three hundred twelve of 454 (68.7%) respondents (271/378 [71.7%] interventionalists, 41/76 [53.9%] non-interventionalists,

Indexed as

endovascular treatmentEVTmechanical thrombectomymedium vessel occlusionMeVO

Identifiers

PMID41137680
PMCPMC12553542

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.