Evidence map›Paper›PMID 41137667›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2025

Low Driveline Infection Rates in Patients With a Novel Fully Magnetically Levitated Ventricular Assist Device.

Xianqiang Wang, Xingtong Zhou, Haibo Chen, Haotian Zhang, Yanming Zhang, Yong Cui, Keli Huang, Zhengdong Hua, Yang Yan, Mi Zhou and 6 more

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06878456 (Incidence and Management of Driveline Infection in Patients with CH-VAD), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06878456 completednot on this map

Incidence and Management of Driveline Infection in Patients with CH-VAD: a Multi-centre, Observational Study

TypeobservationalSponsorChina National Center for Cardiovascular DiseasesRan2017 to 2024Enrolled181ConditionsDriveline Infection
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xianqiang WangCentre of Cardiac Surgery in Adults, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Xingtong ZhouCentre of Cardiac Surgery in Adults, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Haibo ChenCentre of Cardiac Surgery in Adults, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Haotian ZhangCentre of Cardiac Surgery in Adults, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yanming ZhangCentre of Cardiac Surgery in Adults, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yong CuiDepartment of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China.
Keli HuangDepartment of Cardiac Surgery, Sichuan Provincial People's Hospital, Chengdu, 610072, China.
Zhengdong HuaDepartment of Cardiac Surgery, Asia Heart Hospital, Wuhan, 430022, China.
Yang YanDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.ORCID 0000-0001-7167-0261
Mi ZhouDepartment of Cardiovascular Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
Qiang ZhaoDepartment of Cardiovascular Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.ORCID 0000-0002-8930-3854
Xiaoning SunDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Chunsheng WangDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhenwei GeDepartment of Cardiovascular Surgery, Henan Provincial Chest Hospital, Zhengzhou, 450003, China.
Aiqiang DongDepartment of Cardiovascular Surgery, Zhejiang University College of Medicine Second Affiliated Hospital, Hangzhou, 310009, China.
Shengshou HuCentre of Cardiac Surgery in Adults, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.ORCID 0009-0003-7192-1149

Funding

Beijing Outstanding Young Scientist Program 2024-BZZQ01
6 · The paper itself

Abstract

objectivesDriveline infection remains a major complication of long-term ventricular assist device therapy. Previous studies have associated the risk of infection with driveline design and physical properties. The CH-VAD is a fully magnetically levitated pump with an ultrathin (diameter 3.3 mm), highly flexible driveline designed to reduce infection risk. This study was conducted to assess the incidence, risk factors, and approaches to prevention and management of driveline infection in CH-VAD patients (NCT06878456).

methodsAll patients who underwent CH-VAD implantation between June 2017 and October 2024 at 9 centres were retrospectively analysed. Data related to clinical characteristics, surgical procedures, and driveline infection prevention and management details were collected, and risk factors were analysed.

resultsA total of 181 consecutive patients were included, with a median age of 56 years and 86% male. During a median support duration of 1.6 years, driveline infections occurred in 20 out of 181 patients (11.0%). Twenty-six events were observed, corresponding to a rate of 0.07 events per patient-year. Cumulative incidence of the first driveline infection was 2.8% at 6 months, 5.6% at 12 months, and 8.5% at 24 months. Frequent dressing changes were found to be significantly associated with increased driveline infection risk (HR 3.773, P = .022).

conclusionsPatients treated with CH-VADs experienced an encouraging low rate of driveline infection, considered among the lowest reported for durable ventricular assist devices. These findings have implications for both clinical management and driveline design.

Indexed as

Heart-Assist DevicesHeart FailureProsthesis-Related InfectionsAdultAgedFemaleHumansIncidenceMaleMiddle AgedProsthesis DesignRetrospective StudiesRisk Factorsadvanced heart failureCH-VADdriveline infectionleft ventricular assist device

Identifiers

PMID41137667
PMCPMC12673059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.