Evidence map›Paper›PMID 41137629›Full record

Trial reportAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Multi-site video-based assessment with the NACC UDS-Version 3 battery: Design and participant experience in the V-Cog study.

Bonnie C Sachs, Lauren A Latham, Scott Isom, Lindsay R Clark, Suzanne Craft, Kevin Duff, Mark A Espeland, Sarah Tomaszewski Farias, Sarah A Gaussoin, Felicia C Goldstein and 11 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Bonnie C SachsWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Lauren A LathamWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Scott IsomWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Lindsay R ClarkUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Suzanne CraftWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Kevin DuffOregon Health and Science University, Portland, Oregon, USA.
Mark A EspelandWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Sarah Tomaszewski FariasUniversity of California Davis School of Medicine, Sacramento, California, USA.
Sarah A GaussoinWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Felicia C GoldsteinEmory University School of Medicine, Atlanta, Georgia, USA.
Benjamin M HampsteadUniversity of Michigan, Ann Arbor, Michigan, USA.
Suman JayadevUniversity of Washington, Seattle, Washington, USA.
Gregory A JichaUniversity of Kentucky College of Medicine, Lexington, Kentucky, USA.
Walter A KukullUniversity of Washington, Seattle, Washington, USA.
Xiaoyan Iris LengWake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Dawn Mechanic-HamiltonPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Judith NeugroschlMount Sinai School of Medicine, New York, New York, USA.
Kathryn V PappMass General Brigham, Harvard Medical School, Boston, Massachusetts, USA.
Andrew J SaykinIndiana Alzheimer's Disease Research Center and the Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Margaret C SewellMount Sinai School of Medicine, New York, New York, USA.
Stephen R RappWake Forest University School of Medicine, Winston Salem, North Carolina, USA.

Funding

National Alzheimer's Coordinating CenterU24AG072122 · NIA · UNIVERSITY OF WASHINGTON · PI STEPHENS, KARI A · 2021 to 2025
$45.8M
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie · 2019 to 2026
$36.5M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI LEON LENCHIK · 2002 to 2026
$36.4M
Wisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sanjay Asthana · 2019 to 2026
$34.5M
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Margaret Sewell · 2020 to 2026
$31.0M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Amanda D. Boyd · 2020 to 2026
$29.0M
The Goizueta Alzheimer's Disease Research CenterP30AG066511 · NIA · EMORY UNIVERSITY · PI ALLAN I LEVEY · 2020 to 2026
$29.0M
Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
Research Education ComponentP30AG072931 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Henry L Paulson · 2021 to 2026
$26.5M
UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Charles DeCarli, Rachel A Whitmer · 2021 to 2026
$25.2M
Research Education ComponentP30AG072979 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVID A WOLK · 2021 to 2026
$24.8M
Wake Forest University School of Medicine Alzheimer's Disease Research CenterP30AG072947 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SUZANNE CRAFT · 2021 to 2026
$24.3M
NIA NIH HHS K23 AG065499NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG062421NIA NIH HHS P30 AG062715NIA NIH HHS P30 AG066509NIA NIH HHS P30 AG066511NIA NIH HHS P30 AG066514NIA NIH HHS P30 AG066518NIA NIH HHS P30 AG072931NIA NIH HHS P30 AG072946NIA NIH HHS P30 AG072947NIA NIH HHS P30 AG072972NIA NIH HHS P30 AG072976NIA NIH HHS P30 AG072979NIA NIH HHS R01 AG075959NIA NIH HHS R01AG075959NIA NIH HHS U24 AG072122
6 · The paper itself

Abstract

introductionVideo-based cognitive testing is becoming more common. The 'VCog' study aims to evaluate the validity, feasibility, and acceptability of a standardized video-administered cognitive research battery.

methodsTwelve Alzheimer's Disease Research Centers (ADRCs) administered, in randomized order, an in-person and video-adapted Uniform Data Set Version 3 (UDSv3) cognitive assessment battery to participants with normal cognition (n = 156), mild cognitive impairment (MCI; n = 230), and dementia (n = 77). Acceptability of technology and participant experience completing video testing was assessed.

resultsOf 463 participants (mean age 75.1 years, 52.5% female, and 25.5% non-White individuals), most rated video testing as easy (90.0%), convenient (95.3%) and would accept it in future visits (75.5%). Greater cognitive impairment was associated with more difficulty with setup and use of video. Staff rated most administrations as producing valid data (94.8%). DISCUSSION: Video-based research cognitive testing with an adapted UDSv3 battery is feasible and well-accepted among older adults with and without cognitive impairment. HIGHLIGHTS: The COVID-19 pandemic increased the need for video-administered cognitive assessments in Alzheimer's Disease Research Centers (ADRCs) . Feasibility, acceptability, and validity of video cognitive testing were evaluated. Participant experience and examiner evaluations of data validity were positive. Video assessment may extend the ADRCs reach to otherwise unreachable participants.

Indexed as

Alzheimer DiseaseCognitive DysfunctionDementiaNeuropsychological TestsVideo RecordingAgedAged, 80 and overCOVID-19Feasibility StudiesFemaleHumansMaleReproducibility of ResultsAlzheimer's disease (AD)Alzheimer's Disease Research Centerdementiamild cognitive impairmentremote assessmenttelemedicineteleneuropsychologyvideo assessment

Identifiers

PMID41137629
PMCPMC12552888

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.