Evidence map›Paper›PMID 41137524›Full record

ArticleThe Journal of dermatology2026

Combined Maxacalcitol/Betamethasone Butyrate Propionate Ointment Possesses Long-Term Sustained Effects of Inducing Regulatory T Cells and Downregulating the Th17 Response, Even After Discontinuation of Its Application in Imiquimod-Induced Psoriasiform Dermatitis.

Teruo Shimizu, Masahiro Kamata, Hideya Uratsuji, Yoshiki Okada, Ayu Watanabe, Azusa Hiura, Yayoi Tomura, Yayoi Tada

Abstract read
In one paragraph

Article in The Journal of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Teruo ShimizuDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
Masahiro KamataDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0976-4982
Hideya UratsujiMaruho Co., Ltd., Osaka, Japan.
Yoshiki OkadaDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
Ayu WatanabeDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
Azusa HiuraDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
Yayoi TomuraDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
Yayoi TadaDepartment of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3743-135X

Funding

Maruho Co., Ltd.
6 · The paper itself

Abstract

We often experience sustained improvement, even after discontinuation of treatment in psoriasis lesions treated with topical vitamin D

Indexed as

BetamethasoneCalcitriolPsoriasisTh17 CellsT-Lymphocytes, RegulatoryAdministration, CutaneousAnimalsDisease Models, AnimalDown-RegulationDrug CombinationsDrug Therapy, CombinationFemaleHumansImiquimodMiceMice, Inbred BALB CBetamethasoneCalcitriolDrug CombinationsImiquimodmaxacalcitolOintmentsbetamethasone butyrate propionateinterleukin‐10interleukin‐17maxacalcitolpsoriasisregulatory T cells

Identifiers

PMID41137524
PMCPMC12784800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.