ArticleAntimicrobial resistance and infection control2025
Understanding Serratia bockelmannii transmission during a neonatal intensive care unit outbreak: a combined genotyping and case-control study.
Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Genomic pitfalls in hospital surveillance: unexpected Enterobacter cloacae clustering without epidemiological link highlights the need for cautious core genome MLST analysis interpretation.Antimicrobial resistance and infection control · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSerratia marcescens complex (SMC) is a group of opportunistic pathogens frequent in neonatal intensive care unit (NICU) outbreaks. We report a seven-month NICU outbreak of multidrug-resistant (MDR) SMC strain and assess the acquisition risk factors.
methodsBacterial isolates were sequenced using Illumina technology and profiled for antimicrobial resistance (AMR). Cases (culture positive for SMC) were compared with birth date and ward-matched controls (SMC negative) to identify clinical and environmental factors associated with SMC acquisition.
resultsA single strain of Serratia bockelmannii caused 42 cases from June 2022 to January 2023. All sequenced isolates (n = 49) carrued the same AMR genes, while the antibiogram (n = 32) assigned 15 strains as MDR, and 17 as non-MDR. The outbreak strain was recovered from ward surfaces and an analytical study revealed that beds used by several cases increased the acquisition odds by 3.27 (95%CI 1.71-8.77, p-value = 0.003) after adjusting for sex and length of stay.
conclusionsThe genomic typing was pivotal in confirming clonality across S. bockelmannii isolates with varied antibiograms, and identifying the bacterial species. Serratia bockelmannii should be considered during SMC outbreaks. Incubator-related within-ward transmission highlights the need for tailored risk assessments and disinfection protocols to prevent pathogen transmission and to improve infection prevention protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.