Evidence map›Paper›PMID 41137154›Full record

ArticleTrials2025

Supporting the professional development of trial managers: how can you help?

E J Mitchell, C Arundel, D Babalis, S Connolly, L Constable, K Goodman, L Stylianou, J Taylor, N Wakefield, S Williams and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

E J MitchellNottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK. Eleanor.mitchell@nottingham.ac.uk.
C ArundelYork Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, UK.
D BabalisImperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK.
S ConnollyRoyal Marsden Clinical Trials Unit, The Royal Marsden NHS Foundation Trust, London, UK.
L ConstableCentre for Healthcare Randomised Trials (CHaRT), University of Aberdeen, Aberdeen, UK.
K GoodmanCentre for Healthcare Randomised Trials (CHaRT), University of Aberdeen, Aberdeen, UK.
L StylianouDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
J TaylorBristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK.
N WakefieldNottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK.
S WilliamsSouthampton Clinical Trials Unit, School of Medicine, University of Southampton, Southampton, UK.
F WolstenhulmeNewcastle Clinical Trials Unit, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical trial managers are central to the successful design and delivery of clinical trials, making them crucial within the research landscape. Yet, despite their vital contribution, many trial managers report feeling undervalued, under-supported, and insufficiently recognised for the expertise they bring to their teams. Unlike other research roles, there is no clearly defined career pathway for trial managers, and opportunities for professional growth are often limited. In the UK, those working on academic-led trials are usually employed within universities or NHS trusts, frequently based in UKCRC-registered Clinical Trials Units. In this article, we provide practical guidance for both trial managers and their employers on how to strengthen professional development opportunities and better support this essential workforce.

Indexed as

Administrative PersonnelClinical Trials as TopicResearch PersonnelStaff DevelopmentHumansProfessional RoleUnited KingdomClinical trialsProfessional developmentTrial management

Identifiers

PMID41137154
PMCPMC12553290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.