Evidence map›Paper›PMID 41137083›Full record

ArticleBorderline personality disorder and emotion dysregulation2025

Latent class analysis of women with borderline personality disorder: the role of adverse childhood experiences in impulsivity, emotional dysregulation, and neurocognitive profiles.

Horus Laffite, J A Díaz-Garrido, J L Ordóñez-Carrasco, J L Hernández-Fleta, V Martínez-Loredo

Abstract read
In one paragraph

Article in Borderline personality disorder and emotion dysregulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Horus LaffiteUniversity of Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria, Spain. hlafcab@gmail.com.
J A Díaz-GarridoUniversity of Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria, Spain.
J L Ordóñez-CarrascoDepartment of Psychology and Sociology, University of Zaragoza, Teruel, Spain.
J L Hernández-FletaUniversity of Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria, Spain.
V Martínez-LoredoDepartment of Psychology, University of Oviedo, Oviedo, Spain.

Funding

Fundación Canaria Instituto de Investigación Sanitaria de Canarias ENF23/18
6 · The paper itself

Abstract

introductionBorderline personality disorder (BPD) is a complex psychiatric condition strongly associated with adverse childhood experiences (ACEs). This study examined how childhood trauma interacts with impulsivity, emotion dysregulation, and cognitive functioning to identify distinct clinical subtypes in women with BPD and inform personalized treatment strategies. MATERIALS AND

methodsIn this cross-sectional study, 231 women with BPD completed standardized assessments of childhood trauma (CTQ-SF), impulsivity (Barratt Impulsiveness Scale), and emotion regulation (DERS-SF), along with a neuropsychological battery. An exploratory latent class analysis identified subgroups based on trauma exposure and clinical features. Between-class differences in impulsivity, emotion regulation, and cognitive functioning were examined using ANOVA.

resultsFive distinct clinical profiles emerged. The most severe classes—characterized by continuous sexual abuse (17.3%) and early sexual abuse with polysubstance use (25.1%)—showed the highest impulsivity, severe emotion regulation difficulties, and deficits in attention, working memory, and cognitive flexibility. A low-severity class with early sexual abuse (13.4%) exhibited moderate emotion regulation challenges without cognitive impairments. In contrast, two classes without sexual abuse—minimal trauma or violence (31.6%) and violence with substance use (12.6%)—demonstrated better emotional and cognitive functioning, with the low-trauma group displaying the lowest impulsivity and symptom severity.

conclusionsThese findings underscore the importance of trauma-informed and cognitively tailored interventions for enhancing therapeutic outcomes in women with BPD. Recognizing the interplay among trauma, impulsivity, emotion dysregulation, and neurocognition may support more effective treatment planning and resource allocation.

Indexed as

Adverse childhood experienceBorderline personality disorderClinical profileCognitive functionEmotion regulationImpulsivityLatent class

Identifiers

PMID41137083
PMCPMC12553218

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.