ArticleBMC oral health2025
Ligneous gingivitis: diagnostic and management challenges in a rare case.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Correction: Ligneous gingivitis: diagnostic and management challenges in a rare case.BMC oral health · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLigneous gingivitis (LG) is a rare manifestation of plasminogen deficiency characterized by woody fibrin-rich pseudomembranes, recurrent ulceration, and progressive periodontal destruction CASE PRESENTATION: We report a 16-year-old female with hypothyroidism who presented with persistent gingival lesions and tooth mobility since early childhood after a mumps infection. Clinical and radiographic evaluation revealed generalized alveolar bone destruction. Histopathology confirmed LG with fibrinoid deposits. Hematological analysis showed markedly reduced plasminogen levels, measured using an ELISA-based assay, confirming the systemic deficiency. The patient was referred for ophthalmologic and genetic evaluation, targeting PLG gene mutations (K19E hotspot). She received chlorhexidine therapy with improved ulceration and reduced bleeding. At three-month follow-up, the lesions remained stable, and no ocular involvement was observed.
conclusionsThis case illustrates diagnostic challenges, differential considerations with aggressive periodontitis, and emphasizes the need for early recognition, multidisciplinary management, and systemic treatment to prevent severe complications such as blindness, infertility, or progressive periodontal morbidity.
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