Evidence map›Paper›PMID 41137023›Full record

ArticleJournal of orthopaedic surgery and research2025

Factors influencing the quality of life following posterior approach surgical treatment in adolescents with idiopathic scoliosis: A 2-year follow-up study.

Zhengye Zhao, Aoran Maheshati, Xueyi Zhang, Di Liu, Terry Jianguo Zhang, Nan Wu

Abstract read
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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhengye Zhao *Department of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.ORCID http://orcid.org/0000-0002-1663-0467
Aoran Maheshati *Department of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.ORCID http://orcid.org/0000-0001-8445-1869
Xueyi Zhang *Beijing Key Laboratory of Big Data Innovation and Application for Skeletal Health Medical Care, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.ORCID http://orcid.org/0000-0001-8097-112X
Di LiuDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.ORCID http://orcid.org/0000-0002-5803-7223
Terry Jianguo ZhangDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China. jgzhang_pumch@yahoo.com.ORCID http://orcid.org/0000-0003-3129-5190
Nan WuDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China. dr.wunan@pumch.cn.ORCID http://orcid.org/0000-0002-9429-2889

Funding

CAMS Innovation Fund for Medical Sciences 2021-I2M-1-051National High Level Hospital Clinical Research Funding 2022-PUMCH-C-033National High Level Hospital Clinical Research Funding 2022-PUMCH-D-004National Key Research and Development Program of China 2023YFC2507700
6 · The paper itself

Abstract

purposeSurgical intervention is the preferred approach to prevent further progression of deformity for patients with adolescent idiopathic scoliosis (AIS); among existing surgeries, posterior spinal fusion is predominant. The minimal clinically important difference (MCID) of the total score of the Scoliosis Research Society (SRS)-22r questionnaire is an increase of ≥ 0.4 in surgically treated patients. However, to the best of our knowledge, there is no research exploring the factors influencing SRS-22r total scores exceeding MCID at 2 years postoperatively.

methodsPatients who underwent posterior spinal fusion between February 2019 and November 2023 and had a minimum follow-up duration of > 2 years were included. The radiological data and SRS-22r scores were assessed preoperatively and postoperatively. Based on the SRS-22r total scores, the patients were divided into two groups: ‘I’ = Improvement group (∆ Score ≥ 0.4) and ‘NI’ = Non-improvement group (∆ Score < 0.4). Demographic characteristics, radiographic data, and SRS-22r scores were analyzed using chi-square tests and t-tests for comparison. Multivariate logistic regression analysis was used to determine influencing factors.

resultsA total of 66 patients with AIS underwent posterior spinal fusion surgery were included in the study. The major Cobb angle decreased from 52.9 ± 12.3° preoperatively to 12.3 ± 8.6° (p < 0.001) at 2 years postoperatively, while the SRS-22r total score improved from 3.9 ± 0.4 to 4.2 ± 0.5 (p < 0.001). Overall, 32 of 66 of patients (48.5%) achieved MCID. Preoperatively, the Improvement group trended toward a larger Cobb angle (p = 0.042). Postoperatively, patients who achieved a greater Cobb angle correction in degrees were more likely to attain the MCID (p = 0.003).

conclusionPostoperative MCID attainment in patients with AIS is influenced by both the preoperative Cobb angle and the degree of its surgical correction.

Indexed as

Quality of LifeScoliosisSpinal FusionAdolescentFemaleFollow-Up StudiesHumansMaleMinimal Clinically Important DifferenceTime FactorsTreatment OutcomeAdolescent idiopathic scoliosisMinimal clinically important differenceQuality of lifeSRS-22r

Identifiers

PMID41137023
PMCPMC12551350

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.