Trial reportBMC gastroenterology2025
Health education based on precede-proceed model in eradication evaluation of Helicobacter pylori infection: a retrospective cohort study.
Trial report in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of kimura-takemoto atrophy classification on first-lineFrontiers in medicine · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesTo investigate the influence of health education based on the precede-proceed model (PPM) on the eradication rate and experience of Helicobacter pylori (H. pylori) infection.
methods200 patients with asymptomatic H. pylori infections were randomly assigned to a PPM group (n = 100) or a control group (n = 100) using the random number table method based on the time of their medical records. The control group received modified bismuth quadruple therapy (BQT), while the PPM group received modified BQT and health education based on the PPM. Completion rate, eradication rate, drug-related adverse events (AEs), discontinuation rate due to AEs, reexamination rate, recurrence rate, H. pylori knowledge scores, and satisfaction with medical experience were evaluated.
resultsThe treatment completion rate was 96% vs. 84% (P<0.05), the reexamination rate was 93% vs. 79% (P<0.05), the eradication rate according to intention-to-treat (ITT) was 83% vs. 69% (P<0.05), according to per-protocol (PP) was 89.25% vs. 87.34% (P>0.05) in the PPM and control groups, respectively. The recurrence rate was lower in the PPM group than in the control group (2.41% vs. 5.80%, P>0.05); the drug-related AEs were 14% vs. 16%(P>0.05), the discontinuation rate due to AEs was 14.3% vs. 37.5%(P>0.05) in the PPM and control groups, respectively. After treatment, the mean H. pylori knowledge scores were significantly higher in the PPM than in the control groups; the mean knowledge scores of the recurrent patients were significantly lower than those of the non-recurrent patients (P<0.001). Satisfaction with the medical experience was significantly higher in the PPM group than in the control group (P<0.001).
conclusionsHealth education based on the PPM can effectively improve the completion rate of H. pylori eradication treatment, the eradication rate of the ITT analysis, the reexamination rate, and patient compliance, significantly improving patients' knowledge of H. pylori and their experience.
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