Evidence map›Paper›PMID 41136852›Full record

ReviewAdvances in experimental medicine and biology2025

Viral Safety.

Ken Kono, Satoshi Yasuda, Yoji Sato

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ken KonoDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Satoshi YasudaDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.
Yoji SatoNational Institute of Health Sciences, Kawasaki, Kanagawa, Japan. yoji@nihs.go.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral safety is an extremely important issue for the clinical application of cell therapy products. The viral contamination of products can lead to serious adverse events in patients treated with them. Therefore, it is strongly recommended to evaluate the viral safety of products using the most advanced science and technology available at the time, based on scientific rationality. We are also obligated to respond to society's strong interest in and social demand for public health preservation. Because various types of cell therapy products have been developed, some measures to ensure viral safety for each product are common, and others should be addressed on a case-by-case basis. This chapter outlines the basic approach for viral safety confirmation for cell therapy products and introduces our recent work on viral safety using the next-generation sequencer.

Indexed as

Cell- and Tissue-Based TherapyVirus DiseasesVirusesHumansEndogenous retrovirusICH Q5ANext-generation sequencerNucleic acid sequenceViral safety

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.