ArticleJournal of computer-aided molecular design2025
In vitro and in silico evaluation of synthesized 4-Anilinoquinazoline derivatives as potential anticancer agents.
Article in Journal of computer-aided molecular design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
Twenty-three 4-anilinoquinazoline derivatives were successfully synthesized, including six new compounds (8, 9, 12, 17, 19, 20) and seventeen known compounds. Seventeen derivatives (10-26) were evaluated for cytotoxic activity against three cancer cell lines (A549, HepG2, and SH-SY5Y) using the MTT assay. The results showed that compound 13 exhibited high selectivity toward the SH-SY5Y cell line with an IC
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